Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Dementia » Alzheimer Disease
Diseases [C] » Nervous System Diseases [C10] » Neurodegenerative Diseases » Tauopathies » Alzheimer Disease
Psychiatry and Psychology [F] » Mental Disorders [F03] » Neurocognitive Disorders » Dementia » Alzheimer Disease
Description
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) MeSH
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Approved Indicated Drugs (23)
Phase 4 Indicated Drugs (46)
Phase 3 Indicated Drugs (91)
Phase 2 Indicated Drugs (217)
Phase 1 Indicated Drugs (156)
Other Experimental Indicated Drugs (46)
Organization Involved with Phase 4 Indications (107)
Abarbanel Mental Health Center
American Health Assistance Foundation
Associacao Fundo de Incentivo a Psicofarmcologia
Center Abarbanel Mental Health
Daewoong Pharmaceutical Co. LTD.
Fisher Center for Alzheimer's Research Foundation
Fundação de Amparo à Pesquisa do Estado de São Paulo
Hospital Universitario Arnau de Vilanova de Lleida
Icahn School of Medicine at Mount Sinai
John Douglas French Foundation
Kingshill Research Centre, Victoria Hospital, Swindon
Moorgreen Hospital, Southampton
National Institute of Mental Health (NIMH)
National Institute on Aging (NIA)
National Institutes of Health (NIH)
Queen Elizabeth Hospital NHS Foundation Trust
St. Joseph's Hospital and Medical Center - Phoenix, Arizona
Taiwanese Society of Psychiatry
Technical University of Munich
The University of Texas, Dallas
University of California, Los Angeles
University of California, San Diego
Organization Involved with Phase 3 Indications (137)
Accelerating Medicines Partnership
Alzheimer's Clinical Trial Consortium (ACTC)
Alzheimer’s Drug Discovery Foundation
Alzheimer's Therapeutic Research Institute
Aristotle University of Thessaloniki
Assistance Publique - Hôpitaux de Paris
Association France Alzheimer Et Maladies Apparentées
Groupement Interrégional de Recherche Clinique et d'Innovation Est
Hamilton Health Sciences Corporation
Jiangsu Sheneryang High-tech Co., Ltd
Katholieke Universiteit Leuven
National Center for Complementary and Integrative Health (NCCIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
National University of Ireland
Netherlands Alzheimer Foundation
Office of Dietary Supplements (ODS)
Oregon Health and Science University
Palo Alto Veterans Institute for Research
Philipps University of Marburg
Shanghai Greenvalley Pharmaceutical Co., Ltd.
Organization Involved with Phase 2 Indications (232)
A2 Healthcare Taiwan Corporation
Ageless Regenerative Institute
Alanya Alaaddin Keykubat University
Alzheimer Forschungsinitiative e.V.
American Federation for Aging Research
American Society Of Thermalism And Climatology Inc
Avon and Wiltshire Mental Health Partnership NHS Trust
Beijing Bionovo Medicine Development Co., Ltd.
BHT Lifescience Austrailia Pty Ltd.
Blanchette Rockefeller Neurosciences Insitute
Burke Medical Research Institute
Case Western Reserve University
Cellular Biomedicine Group Ltd.
Chase Pharmaceuticals Corporation
Chinese University of Hong Kong
Clinical Research Services Turku
Daehwa Pharmaceutical Co., Ltd.
Eastern Virginia Medical School
EuroEspes Biomedical Research Center
Feinstein Institute for Medical Research
Hampshire Hospitals NHS Foundation Trust
Huntington Medical Research Institutes
Institute for Neurodegenerative Disorders
Institute for the Study of Aging (ISOA)
I.R.C.C.S. Fondazione Santa Lucia
Jaslok Hospital and Research Centre, Mumbai, India
Kawasaki Medical School Hospital
Korea Health Industry Development Institute
Mindful Diagnostics and Therapeutics
Mindful Diagnostics and Therapeutics, LLC
National Center for Research Resources (NCRR)
National Cheng Kung University
National University of Singapore
Northumberland, Tyne and Wear NHS Foundation Trust
Oregon Partnership for Alzheimer's Research
Paul Beeson Faculty Scholars Program
People's Liberation Army of China
Pharmaceutical Research Associates, Inc. (PRA)
Pharmacology Research Institute
Pharmacology Research Institute, Northridge
Rock Creek Pharmaceuticals, Inc.
Shahid Beheshti University of Medical Sciences
South China Research Center for Stem Cell and Regenerative Medicine
Taipei Veteran General hospital
The Florey Institute of Neuroscience and Mental Health
The John A. Hartford Foundation
The Memory Enhancement Center of America, Inc.
Tokyo Dementia Care Research and Training Center
Tokyo Metropolitan Geriatric Medical Center
University of Alabama, Birmingham
University of Colorado, Denver
University of Rome Tor Vergata
University of Texas, San Antonio
Vincent van Gogh voor Geestelijke Gezondheidszorg
Organization Involved with Phase 1 Indications (92)
Atlanta Center for Medical Research
Boryung Pharmaceutical Company
Collaborative Neuroscience Network
Comprehensive Clinical Development, Inc.
Fundación Teófilo Hernando, Spain
German Center for Neurodegenerative Diseases (DZNE)
Helmholtz Centre for Infection Research
Mashhad University of Medical Sciences
Memorial Sloan-Kettering Cancer Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Neuraltus Pharmaceuticals, Inc.
NeuroGenetic Pharmaceuticals Inc
Neurological Associates of West Los Angeles
Northern Ontario School of Medicine
Organization Involved with Other Experimental Indications (43)
Centre Hospitalier Princesse Grace
Centre Hospitalier Universitaire de Nīmes
Chinese Academy of Medical Sciences
Institut Hospital del Mar d'Investigacions Mèdiques
Institut National de la Santé Et de la Recherche Médicale, France
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UMLS Data
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