Active Ingredient History

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Ascorbic acid (vitamin C) is a water-soluble vitamin. It occurs as a white or slightly yellow crystal or powder with a slight acidic taste. Ascorbic acid is an electron donor, and this property accounts for all its known functions. As an electron donor, ascorbic acid is a potent water-soluble antioxidant in humans. Ascorbic acid acts as an antioxidant under physiologic conditions exhibiting a cross over role as a pro-oxidant in pathological conditions. Oxidized ascorbic acid (dehydroascorbic acid (DHA) directly inhibits IkappaBalpha kinase beta (IKKbeta) and IKKalpha enzymatic activity in vitro, whereas ascorbic acid did not have this effect. These findings define a function for vitamin C in signal transduction other than as an antioxidant and mechanistically illuminate how vitamin C down-modulates NF-kappaB signaling. Vitamin C is recommended for the prevention and treatment of scurvy. Its parenteral administration is desirable for patients with an acute deficiency or for those whose absorption of orally ingested ascorbic acid (vitamin c) is uncertain. Symptoms of mild deficiency may include faulty bone and tooth development, gingivitis, bleeding gums, and loosened teeth. Febrile states, chronic illness, and infection (pneumonia, whooping cough, tuberculosis, diphtheria, sinusitis, rheumatic fever, etc.) increase the need for ascorbic acid (vitamin c). Hemovascular disorders, burns, delayed fracture and wound healing are indications for an increase in the daily intake.   NCATS

More Chemistry
  • Mechanisms of Action: Missing data
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral, Parenteral
  • Pro Drug: No

Drug Pricing (per unit)

United States

$1.2670 - $111.7036
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

acide ascorbique | ácido ascórbico | acidum ascorbicum | acidum ascorbinicum | ascorbate | ascorbic acid | ascorbic acid, monosodium salt | ascorbic acid (vit c) | ascorbicap | ascorbin | ascorbinsäure | ascur | bassett's | calcium ascorbate | cebione | cecon | cenolate | cetane | cetane-caps tc | cevalin | cevex | cevitamic acid | chick pea extractvitamin c, l-leucine, vegetable capsule (hypromellose) | e300 | e301 | enantic acid | haliborange | kaprylsaeure | l-ascorbate | l-(+)-ascorbic acid | l-ascorbic acid | lithium octanoate | n-capric acid | n-caprylic acid | n-decanoic acid | neo-fat 8 | peg-ascorbate | redoxon | redoxon c | redoxon chew-c | redoxon slow release | sodium ascorbate | sodium octanoate | top c | vital life | vitamin c | vitamins c

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