Active Ingredient History

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Nicotine is a natural alkaloid obtained from the dried leaves and stems of the nightshade family of pants, such as Nicotiana tabacum and Nicotiana rustica, where it occurs in concentrations of 0.5-8%. Cigarette tobacco varies in its nicotine content, but common blends contain 15-25 mg per cigarette, with a current trend towards lower levels. Nicotine is highly addictive substance, it exhibits a stimulant effect when adsorbed at 2 mg. Administration of higher doses could be harmful. Action of nicotine is mediated by nicotinic cholinergic receptors. Nicotine binds to the interface between two subunits of the receptors, opens the channel and allows the entry of sodium or calcium. The principal mediator of nicotine dependence is α4β2 nicotine receptor.   NCATS

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Drug Pricing (per unit)

United States

$0.0969 - $110.2900

Australia

$0.1020 - $21.9642
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

3-(2-(n-methylpyrrolidinyl))pyridine | 3-(n-methylpyrollidino)pyridine | commit | habitrol | l-nicotine | l(−)-nicotine | nicabate | nicoderm | nicoderm cq | nicopass | nicopatch | nicorette | nicorette invisi | nicotine | (-)-nicotine | (−)-nicotine | nicotine betadex | nicotine bitartrate | nicotine bitartrate anhydrous | (-)-nicotine hydrogen tartrate salt | nicotinell classic | nicotinell support | nicotinell tts 10 | nicotinell tts 20 | nicotinell tts 30 | nicotine polacrilex | nicotrol | nicotrol inhaler | nicotrol ns | niquitin | niquitin clr | niquitin minis cherry | niquitin minis mint | niquitin minis orange | niquitin mint | niquitin pre-quit | niquitin strips mint | prostep | (s)-3-(1-methylpyrrolidin-2-yl)pyridine | (s)-3-(n-methylpyrrolidin-2-yl)pyridine | (s)-nicotine | (s)-(−)-nicotine | stoppers | stubit | thrive

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