Active Ingredient History
Doxycycline hyclate (Vibramycin, Periostat, Vibra-Tabs) is salt of tetracycline antibiotic Doxycycline, that used to treat many kinds of infections, like dental, skin, respiratory, and urinary tract infections. It also treats acne, Lyme disease, malaria, and certain sexually transmitted diseases. Doxycycline hyclate is a light-yellow crystalline powder which is soluble in water, while doxycycline monohydrate is very slightly soluble in water. Doxycycline is bacteriostatic, inhibiting bacterial protein synthesis due to disruption of transfer RNA and messenger RNA at ribosomal sites. Doxycycline hyclate is indicated for use in the treatment of chronic adult periodontitis for a gain in clinical attachment, reduction in probing depth, and reduction in bleeding on probing. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Bartonella Infections (approved 1967)
Campylobacter Infections (approved 1967)
Granuloma Inguinale (approved 1967)
Periodontitis (approved 1967)
Rocky Mountain Spotted Fever (approved 1967)
Typhus, Epidemic Louse-Borne (approved 1967)
Abortion, Induced (Phase 4)
Abortion, Septic (Phase 4)
Acneiform Eruptions (Phase 4)
Aggressive Periodontitis (Phase 1/Phase 2)
Alopecia (Phase 4)
Alzheimer Disease (Phase 3)
Amyloidosis (Phase 3)
Androgens (Phase 3)
Aneurysm (Phase 2)
Angiomatosis (Phase 1)
Anterior Wall Myocardial Infarction (Phase 3)
Anthrax (Phase 2)
Antibiotic Prophylaxis (Phase 3)
Aortic Aneurysm, Abdominal (Phase 2)
Arteriovenous Malformations (Phase 1)
Arthritis, Reactive (Phase 3)
Arthroplasty (Phase 3)
Autoimmune Diseases (Phase 4)
Bacterial Infections (Phase 4)
Blepharitis (Phase 4)
Borrelia Infections (Phase 4)
Brain Injuries, Traumatic (Phase 4)
Brain Neoplasms (Phase 1)
Breast Neoplasms (Phase 2)
Bursitis (Phase 4)
Buruli Ulcer (Phase 2)
Carcinoma, Non-Small-Cell Lung (Phase 2)
Cardiomyopathies (Phase 2)
Cardiopulmonary Bypass (Phase 2)
Cardio-Renal Syndrome (Phase 1)
Cardiovascular Diseases (Phase 4)
Cerebral Hemorrhage (Phase 1)
Cerebral Ventriculitis (Phase 1)
Chlamydia (Phase 4)
Chlamydia trachomatis (Phase 4)
Chronic Pain (Phase 4)
Chronic Periodontitis (Phase 3)
Coinfection (Phase 2)
Colitis, Ulcerative (Phase 4)
Colonic Neoplasms (Phase 4)
Colorectal Neoplasms (Phase 3)
Communicable Diseases (Phase 2/Phase 3)
Community-Acquired Infections (Phase 4)
Coronary Aneurysm (Phase 2)
Coronary Artery Bypass (Phase 2)
Coronary Disease (Phase 2)
Coronavirus Infections (Phase 2)
COVID-19 (Phase 4)
Coxiella (Phase 4)
Crohn Disease (Phase 4)
Cystic Fibrosis (Phase 4)
Cystitis, Interstitial (Phase 4)
Cytokine Release Syndrome (Phase 2)
Dental Pulp (Phase 4)
Dermatitis (Phase 2)
Dermatitis, Atopic (Phase 2)
Dermatology (Phase 2)
Diabetes Mellitus (Phase 4)
Diabetes Mellitus, Type 2 (Phase 4)
Diabetic Foot (Phase 2)
Diabetic Retinopathy (Phase 2)
Drug Resistance, Bacterial (Phase 4)
Drugs, Generic (Phase 1)
Dry Eye Syndromes (Phase 4)
Dyspepsia (Phase 3)
Eczema (Phase 2)
Elbow (Phase 1)
Elbow Tendinopathy (Phase 1)
Elephantiasis, Filarial (Phase 3)
Emphysema (Phase 2)
Endocrine System Diseases (Phase 2)
Endometrial Neoplasms (Phase 2)
Endometritis (Phase 4)
Eosinophilia (Phase 2)
Epidermal Cells (Phase 2)
Epistaxis (Phase 4)
Erythema (Phase 4)
Erythema Chronicum Migrans (Phase 4)
Exanthema (Phase 2)
Eye Burns (Phase 2/Phase 3)
Eye Diseases (Phase 1/Phase 2)
Eye Diseases, Hereditary (Phase 2)
Fatigue Syndrome, Chronic (Phase 4)
Fever (Phase 4)
Filariasis (Phase 4)
Gastritis (Phase 3)
General Surgery (Phase 3)
Geographic Atrophy (Phase 2/Phase 3)
Gonorrhea (Phase 4)
Graves Disease (Phase 2)
Graves Ophthalmopathy (Phase 2)
Head and Neck Neoplasms (Phase 1)
Healthy Volunteers (Phase 1)
Heart Failure (Phase 3)
Helicobacter Infections (Phase 3)
Helicobacter pylori (Phase 4)
Hemorrhage (Phase 4)
HIV (Phase 4)
HIV Infections (Phase 4)
Hospitalization (Phase 3)
Hydrocephalus (Phase 1)
Hyperthyroidism (Phase 2)
Idiopathic Pulmonary Fibrosis (Phase 3)
Immune System Diseases (Phase 2)
Immunoglobulin Light-chain Amyloidosis (Phase 2)
Infections (Phase 4)
Inflammation (Phase 4)
Insomnia, Fatal Familial (Phase 2)
Intracranial Aneurysm (Phase 1)
Larynx (Phase 2)
Leishmaniasis, Cutaneous (Phase 3)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 2)
Lichen Planus, Oral (Phase 2)
Lip (Phase 2)
Lung Diseases (Phase 2/Phase 3)
Lyme Disease (Phase 4)
Lyme Neuroborreliosis (Phase 4)
Lymphangioleiomyomatosis (Phase 4)
Lymphedema (Phase 3)
Lymphoma (Phase 3)
Lymphoma, B-Cell, Marginal Zone (Phase 2)
Lymphoma, Follicular (Phase 2)
Lymphoma, Large B-Cell, Diffuse (Phase 2)
Lymphoma, Mantle-Cell (Phase 2)
Lymphoma, Non-Hodgkin (Phase 2)
Lymphoma, T-Cell (Phase 2)
Lymphoma, T-Cell, Cutaneous (Phase 2)
Macular Degeneration (Phase 2)
Malaria (Phase 1)
Mansonelliasis (Phase 2)
Marfan Syndrome (Phase 2)
Meibomian Gland Dysfunction (Phase 4)
Melanoma (Phase 1/Phase 2)
Menstrual Cycle (Phase 3)
Mouth (Phase 2)
Mucocutaneous Lymph Node Syndrome (Phase 2)
Mucositis (Phase 2)
Multiple Sclerosis (Phase 4)
Mycoplasma (Phase 4)
Mycoplasma Infections (Phase 3)
Mycoses (Phase 1)
Mycosis Fungoides (Phase 2)
Myocardial Infarction (Phase 2/Phase 3)
Nasal Polyps (Phase 3)
Neoplasm Metastasis (Phase 1)
Neoplasms (Phase 3)
Neoplasms, Second Primary (Phase 4)
Neurofibromatosis 2 (Phase 1/Phase 2)
Obesity (Phase 4)
Osteoarthritis (Phase 3)
Pain (Phase 2)
Pancreatic Neoplasms (Phase 2)
Parkinson Disease (Phase 2)
Pediatrics (Phase 4)
Pelvic Inflammatory Disease (Phase 2)
Peptic Ulcer (Phase 4)
Periodontal Diseases (Phase 4)
Periodontitis (Phase 4)
Persian Gulf Syndrome (Phase 3)
Pharynx (Phase 2)
Pleural Effusion, Malignant (Phase 2)
Pleural Neoplasms (Early Phase 1)
Polycystic Ovary Syndrome (Phase 3)
Prosthesis-Related Infections (Phase 4)
Pulmonary Disease, Chronic Obstructive (Phase 4)
Pulmonary Emphysema (Phase 4)
Purpura, Thrombocytopenic, Idiopathic (Phase 2/Phase 3)
Q Fever (Phase 4)
Rabies (Phase 4)
Relapsing Fever (Phase 2/Phase 3)
Renal Insufficiency, Chronic (Phase 4)
Reperfusion Injury (Phase 2)
Rhinoscleroma (Phase 1)
Risk-Taking (Phase 3)
Rocky Mountain Spotted Fever (Phase 3)
Rosacea ()
SARS-CoV-2 (Phase 2)
Scrub Typhus (Phase 4)
Seizures (Phase 2)
Severe Acute Respiratory Syndrome (Phase 2)
Sexually Transmitted Diseases (Phase 4)
Sexually Transmitted Diseases, Bacterial (Phase 2/Phase 3)
Sezary Syndrome (Phase 2)
Shoulder Injuries (Phase 4)
Signs and Symptoms (Phase 4)
Sinusitis (Phase 4)
Skin Diseases (Phase 2)
Skin Diseases, Genetic (Phase 2)
Spirochaetales Infections (Phase 2/Phase 3)
ST Elevation Myocardial Infarction (Phase 3)
Stomach Neoplasms (Phase 2)
Subarachnoid Hemorrhage (Phase 1)
Surgical Wound Infection (Phase 3)
Syphilis (Phase 4)
Tennis Elbow (Phase 1)
Therapeutics (Phase 2/Phase 3)
Thoracic Surgery (Phase 3)
Thyroid Diseases (Phase 2)
Thyroid Gland (Phase 2/Phase 3)
Tobacco Use (Phase 4)
Traumatology (Phase 2)
Tuberculosis (Phase 3)
Tuberous Sclerosis (Phase 4)
Unsafe Sex (Phase 3)
Urethritis (Phase 4)
Urinary Bladder, Overactive (Phase 4)
Urticaria (Phase 2)
Uterine Cervicitis (Phase 4)
Uterine Diseases (Phase 2)
Uterine Hemorrhage (Phase 3)
Uterine Neoplasms (Phase 2)
Vaginal Diseases (Phase 4)
Vascular Diseases (Phase 2/Phase 3)
Ventricular Remodeling (Phase 3)
Vomiting (Phase 4)
Waldenstrom Macroglobulinemia (Phase 2)
Wet Macular Degeneration (Phase 2)
Wounds and Injuries (Phase 2)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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