Active Ingredient History

NOW
  • Now
Emtricitabine was discovered by Emory researchers Dr. Dennis C. Liotta, Dr. Raymond F. Schinazi and Dr. Woo-Baeg Choi and licensed to Triangle Pharmaceuticals by Emory University in 1996. Triangle was acquired by Gilead in 2003. Emtricitabine, marketed by Gilead as Emtriva, was first approved by the U.S. Food and Drug Administration in July 2003 for the treatment of HIV infection in combination with other antiretroviral agents. Emtricitabine, a synthetic nucleoside analog of cytidine, is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate. Emtricitabine 5'-triphosphate inhibits the activity of the HIV-1 reverse transcriptase by competing with the natural substrate deoxycytidine 5'-triphosphate and by being incorporated into nascent viral DNA which results in chain termination.   NCATS

  • SMILES: NC1=NC(=O)N(C=C1F)[C@@H]2CS[C@H](CO)O2
  • InChIKey: XQSPYNMVSIKCOC-NTSWFWBYSA-N
  • Mol. Mass: 247.247
  • ALogP: -0.46
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: Yes

Drug Pricing (per unit)

United States

$0.5528 - $17.4549
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( efavirenz (sustiva), tenofovir (viread), emtricitabine (emtriva) - other name: emtricitabine; tenofovir    disoproxil fumarate; efavirenz )
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( emtricitabine (emtriva), tenofovir alafenamide (genvoya), cobicistat (stribild), elvitegravir (vitekta) - other name: elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide )
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( tenofovir (viread), emtricitabine (emtriva), cobicistat (stribild), elvitegravir (vitekta) - other name: cobicistat, elvitegravir, emtricitabine, and tenofovir disoproxil fumarate )
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( tenofovir (viread), emtricitabine (emtriva) - other names: emtricitabine and tenofovir disoproxil fumarate, emtricitabine/tenofovir disoproxil fumarate 200 mg-245 mg oral tablet [truvada], immediate intervention arm truvada in brazil, tenofovir (300mg)/emtricitabine(200mg) [truvada®], tenofovir disoproxil fumarate; emtricitabine, tenofovir disoproxyl fumarate 300 mg plus emtricitabine 200 mg oral tablet )
1-(2-(hydroxymethyl)oxathiolan-5-yl)-5-fluorocytosine | 2',3',5-ftc | 2',3'-dideoxy-5-fluoro-3'-thiacytidine | 2',3'-dideoxy-5-fluoro-3'-thiacytidine, (2s-cis)-isomer | 2'-deoxy-5-fluoro-3'-oxa-4'-thiocytidine | (-)-2'-deoxy-5-fluoro-3'-thiacytidine | 2'-deoxy-5-fluoro-3'-thiacytidine | 2'-deoxy-5-fluoro-3'-thiacytidine, 2s-trans isomer | 2'-deoxy-5-fluoro-3'-thiacytidine, cis-isomer | 2-ftc | (-)-(2r,5s)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine | (2r-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1h)-pyrimidinone | 4-amino-5-fluoro-1-((2r,5s)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1h-pyrimidin-2-one | 4-amino-5-fluoro-1-((2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1h)-one | 524w91 | 5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine | 5-fluoro-1-((2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine | (-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine | bw524w91 | bw 524w91 | bw-524w91 | (-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1h)-pyrimidin-2-one | coviracil | dotfc | efavirenz / emtricitabine / tenofovir disoproxil fumarate | efavirenz / emtricitabine / tenofovir disoproxil maleate | efavirenz / emtricitabine / tenofovir disoproxil, phosphate | efavirenz / emtricitabine / tenofovir disoproxil succinate | elvitegravir / cobicistat / emtricitabine / tenofovir disoproxil fumarate | emtricitabin | emtricitabina | emtricitabine | emtricitabine / rilpivirine hydrochloride / tenofovir alafenamide | emtricitabine / rilpivirine hydrochloride /tenofovir disoproxil fumarate | emtricitabine / tenofovir | emtricitabine / tenofovir alafenamide | emtricitabine / tenofovir disoproxil fumarate | emtricitabine / tenofovir disoproxil maleate | emtricitabine, tenofovir disoproxil phosphate | emtricitabine / tenofovir disoproxil succinate | emtricitabinum | emtricitabline | emtricitagine | emtriva | ftc | (-)-ftc | ftc-(-) | racivir

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