Active Ingredient History
Icosapent is an important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families. EPA can be used for lowering elevated triglycerides in those who are hyperglyceridemic. In addition, EPA may play a therapeutic role in patients with cystic fibrosis by reducing disease severity and may play a similar role in type 2 diabetics in slowing the progression of diabetic nephropathy. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
---|
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
---|
22q11 Deletion Syndrome (Phase 2/Phase 3)
Acne Vulgaris (Phase 3)
Acquired Immunodeficiency Syndrome (Phase 4)
Adenomatous Polyposis Coli (Phase 2/Phase 3)
Adenomatous Polyps (Phase 2/Phase 3)
Aggression (Phase 2/Phase 3)
Aggressive Periodontitis (Phase 2/Phase 3)
Alzheimer Disease (Phase 3)
Amniotic Fluid (Phase 4)
Anemia, Sickle Cell (Phase 2)
Angina Pectoris (Phase 4)
Anorexia (Phase 3)
Antisocial Personality Disorder (Phase 2/Phase 3)
Anxiety Disorders (Phase 3)
Area Under Curve (Phase 1)
Arrhythmias, Cardiac (Phase 4)
Arthralgia (Phase 3)
Arthritis, Rheumatoid (Phase 1)
Asthma (Phase 3)
Atherosclerosis (Phase 4)
Atrial Fibrillation (Phase 4)
Atrial Function, Left (Phase 4)
Autism Spectrum Disorder (Phase 4)
Autistic Disorder (Phase 2)
Barrett Esophagus (Phase 4)
Behavior (Phase 2/Phase 3)
beta-Thalassemia (Phase 2)
Biological Availability (Phase 1)
Bipolar Disorder (Phase 4)
Borderline Personality Disorder (Phase 4)
Brain Injuries, Traumatic (Phase 2)
Breast Neoplasms (Phase 3)
Cachexia (Phase 3)
Carcinoma, Hepatocellular (Phase 4)
Cardiovascular Diseases (Phase 4)
Cataract (Phase 3)
Chagas Cardiomyopathy (Early Phase 1)
Child Development (Phase 4)
Cholangiocarcinoma (Phase 4)
Cholestasis (Phase 3)
Chronic Pain (Early Phase 1)
Chronic Periodontitis (Phase 4)
Cognition (Phase 1/Phase 2)
Cognition Disorders (Phase 2)
Colonic Neoplasms (Phase 3)
Colorectal Neoplasms (Phase 4)
Combat Disorders (Phase 2)
Coronary Artery Disease (Phase 4)
Coronary Disease (Phase 3)
COVID-19 (Phase 4)
Cystectomy (Phase 4)
Cystic Fibrosis (Phase 3)
Death, Sudden, Cardiac (Phase 3)
Defibrillators, Implantable (Phase 4)
Deficiency Diseases (Phase 4)
Dementia, Vascular (Phase 2)
Depression (Phase 3)
Depression, Postpartum (Phase 2)
Depressive Disorder (Phase 3)
Depressive Disorder, Major (Phase 3)
Dermatitis (Phase 1/Phase 2)
Diabetes Mellitus (Phase 4)
Diabetes Mellitus, Type 1 (Phase 1)
Diabetes Mellitus, Type 2 (Phase 4)
Diabetic Neuropathies (Phase 4)
Drugs, Investigational (Phase 2)
Drug Therapy (Phase 3)
Dry Eye Syndromes (Phase 4)
Dyskinesias (Phase 4)
Dyslipidemias (Phase 4)
Dysthymic Disorder (Phase 2)
Eczema (Phase 3)
Eicosapentaenoic Acid (Phase 1/Phase 2)
Endarterectomy, Carotid (Phase 3)
Endocrine System Diseases (Phase 3)
Endothelial Cells (Phase 2)
Epilepsy (Phase 2/Phase 3)
Esophageal Neoplasms (Phase 4)
Executive Function (Phase 2)
Exocrine Pancreatic Insufficiency (Phase 2)
Facial Pain (Phase 1)
Fasting (Phase 1)
Fatigue (Phase 2)
Fatty Acids (Phase 2/Phase 3)
Fatty Acids, Omega-3 (Phase 1)
Fatty Liver (Phase 3)
Feeding and Eating Disorders (Phase 1)
Fetal Growth Retardation (Phase 2)
Fibromyalgia (Phase 2)
Fibrosis (Phase 4)
Flushing (Phase 3)
Gastrointestinal Microbiome (Phase 1/Phase 2)
General Surgery (Phase 3)
Glomerulonephritis, IGA (Phase 4)
Glucose Metabolism Disorders (Phase 3)
Head and Neck Neoplasms (Phase 3)
Healthy Volunteers (Phase 3)
Heart (Phase 4)
Heart Disease Risk Factors (Phase 4)
Heart Diseases (Phase 4)
Heart Failure (Phase 4)
Hemodialysis, Home (Phase 4)
Hemoglobin, Sickle (Phase 2)
Hemorrhage (Phase 2)
Hepatitis C, Chronic (Phase 2)
HIV (Phase 4)
HIV Infections (Phase 4)
Hot Flashes (Phase 4)
Huntington Disease (Phase 3)
Hypercholesterolemia (Phase 4)
Hyperglycemia (Phase 4)
Hyperlipidemia, Familial Combined (Phase 3)
Hyperlipidemias (Phase 4)
Hyperlipoproteinemia Type II (Phase 3)
Hypersensitivity (Phase 3)
Hypertension (Phase 4)
Hypertrophy, Left Ventricular (Phase 4)
Individuality (Phase 4)
Infant, Premature (Phase 4)
Infections (Phase 4)
Infertility (Phase 2)
Infertility, Female (Early Phase 1)
Inflammation (Phase 4)
Insulin Resistance (Phase 3)
Intermittent Claudication (Phase 3)
Ischemic Attack, Transient (Early Phase 1)
Ischemic Stroke (Early Phase 1)
Keratoconjunctivitis Sicca (Phase 2/Phase 3)
Kidney Diseases (Phase 3)
Kidney Failure, Chronic (Phase 4)
Kidney Transplantation (Phase 4)
Laminaria (Phase 3)
Leukemia (Phase 1/Phase 2)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 2)
Lichen Planus, Oral (Phase 2)
Lipid Metabolism Disorders (Phase 2/Phase 3)
Lipoproteins (Phase 4)
Liver Diseases (Phase 1/Phase 2)
Liver Neoplasms (Phase 4)
Lung Diseases (Phase 2)
Lung Neoplasms (Phase 2/Phase 3)
Lupus Erythematosus, Systemic (Phase 4)
Lymphoma (Phase 1/Phase 2)
Lymphoma, Follicular (Phase 2)
Macular Degeneration (Phase 3)
Magnetic Resonance Imaging (Phase 1)
Malnutrition (Phase 4)
Mania (Phase 2)
Memory Disorders (Phase 4)
Menopause (Phase 4)
Mental Disorders (Phase 2)
Metabolic Diseases (Phase 3)
Metabolic Syndrome (Phase 4)
Metabolism (Phase 2)
Migraine Disorders (Phase 4)
Mitral Valve Insufficiency (Phase 4)
Mood Disorders (Phase 2)
Mouth (Phase 2)
Multiple Myeloma (Phase 1/Phase 2)
Multiple Sclerosis (Phase 1/Phase 2)
Multiple Trauma (Phase 1/Phase 2)
Muscles (Phase 4)
Muscular Dystrophy, Duchenne (Phase 2)
Myocardial Infarction (Phase 4)
Myocardial Ischemia (Phase 4)
Neoplasm Metastasis (Phase 3)
Neoplasms (Phase 4)
Neurocognitive Disorders (Phase 4)
Non-alcoholic Fatty Liver Disease (Phase 4)
Obesity (Phase 4)
Obesity, Morbid (Phase 4)
Osteoarthritis (Phase 2/Phase 3)
Overweight (Phase 2/Phase 3)
Pain (Phase 3)
Parenteral Nutrition (Phase 3)
Periodontal Diseases (Phase 2)
Peripheral Arterial Disease (Phase 3)
Peripheral Nerve Injuries (Phase 3)
Peroxidase (Phase 2/Phase 3)
Pharmacokinetics (Phase 1)
Pharmacology (Phase 1/Phase 2)
Phobia, Social (Phase 2)
Postoperative Cognitive Complications (Phase 4)
Postoperative Complications (Phase 2/Phase 3)
Pregnancy (Phase 3)
Pregnancy Complications (Early Phase 1)
Premature Birth (Phase 4)
Premenopause (Phase 3)
Prodromal Symptoms (Phase 4)
Prostatic Neoplasms (Phase 2)
Proteomics (Phase 2)
Psoriasis (Phase 1)
Psychological Distress (Phase 2)
Psychotic Disorders (Phase 4)
Pulmonary Disease, Chronic Obstructive (Phase 2)
Pyelonephritis (Phase 3)
Quality of Life (Phase 2)
Reading (Phase 4)
Renal Insufficiency, Chronic (Phase 2)
Respiratory Distress Syndrome (Phase 3)
Respiratory Tract Infections (Phase 4)
Sarcopenia (Phase 3)
Schizophrenia (Phase 4)
Sepsis (Phase 4)
Shock, Septic (Phase 4)
Short Bowel Syndrome (Phase 1/Phase 2)
Smoldering Multiple Myeloma (Phase 2)
Sprains and Strains (Phase 2)
Squamous Cell Carcinoma of Head and Neck (Phase 3)
Steatitis (Phase 2)
Stomach Neoplasms (Phase 4)
Stress Disorders, Post-Traumatic (Phase 3)
Subarachnoid Hemorrhage (Phase 4)
Substance-Related Disorders (Phase 2)
Systemic Inflammatory Response Syndrome (Phase 4)
Tardive Dyskinesia (Phase 2)
Triglycerides (Phase 4)
Urinary Bladder Neoplasms (Phase 4)
Vascular Diseases (Phase 3)
Vasomotor System (Phase 3)
Vasospasm, Intracranial (Phase 4)
Vitamin D Deficiency (Phase 4)
Wounds and Injuries (Phase 3)
Trial | Phase | Start Date | Organizations | Indications |
---|
Feedback
Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).
Report issue