Active Ingredient History

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Risperidone, a benzisoxazole derivative, is an atypical antipsychotic drug with high affinity for 5-hydrotryptamine (5-HT) and dopamine D2 receptors. It is FDA approved for the treatment of schizophrenia, bipolar mania, irritability associated with autistic disorder. Carbamazepine and other enzyme inducers decrease plasma concentrations of risperidone. Vice versa, Fluoxetine, paroxetine, and other CYP 2D6 enzyme inhibitors increase plasma concentrations of risperidone. Common adverse reactions include increased mortality in elderly patients with dementia-related psychosis, cerebrovascular adverse events, including stroke, in elderly patients with dementia-related psychosis, neuroleptic malignant syndrome, tardive dyskinesia , metabolic Changes (hyperglycemia and diabetes mellitus, dyslipidemia, weight gain), hyperprolactinemia, orthostatic hypotension, leukopenia, neutropenia, agranulocytosis, potential for cognitive and motor impairment, seizures, dysphagia, priapism, disruption of body temperature regulation.   NCATS

  • SMILES: CC1=C(CCN2CCC(CC2)C3=NOC4=C3C=CC(F)=C4)C(=O)N5CCCCC5=N1
  • InChIKey: RAPZEAPATHNIPO-UHFFFAOYSA-N
  • Mol. Mass: 410.4845
  • ALogP: 3.59
  • ChEMBL Molecule:
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Drug Pricing (per unit)

United States

$0.0469 - $44.9800

Australia

$0.0806 - $78.6619
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

r 64,766 | r-64766 | r-64-766 | ripedon | riperidone | rispadal | risperdal | risperdal consta | risperdal consta long acting | risperdal m | risperdal m-tab | risperdal quicklet | risperdone | risperidal | risperidona | risperidone | risperidonum | risperin | rispolept | rispolin | sequinan

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