Active Ingredient History
Lacticaseibacillus casei is an organism that belongs to the largest genus in the family Lactobacillaceae, a lactic acid bacteria (LAB), that was previously classified as Lactobacillus casei-01. This bacteria has been identified as facultatively anaerobic or microaerophilic, acid-tolerant, non-spore-forming bacteria. The taxonomy of this group has been debated for several years because researchers struggled to differentiate between the strains of L. casei and L. paracasei. It has recently been accepted as a single species with five subspecies: L. casei subsp. rhamnosus, L. casei subsp. alactosus, L. casei subsp. casei, L. casei subsp. tolerans, and L. casei subsp. pseudoplantarum. The taxonomy of this genus was determined according to the phenotypic, physiological, and biochemical similarities. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Acute-On-Chronic Liver Failure (Phase 3)
Adenomatous Polyposis Coli (Phase 2)
Allergy and Immunology (Phase 2)
Ascites (Phase 2)
Asthma (Phase 2)
Clostridium Infections (Phase 3)
Colonic Neoplasms (Phase 4)
Colonoscopy (Phase 2)
Constipation (Phase 4)
Crohn Disease (Phase 4)
Deglutition Disorders (Early Phase 1)
Dermatitis, Atopic (Phase 3)
Diarrhea (Phase 4)
Drug Resistance, Bacterial (Phase 2)
Dyspepsia (Phase 1/Phase 2)
Fatty Liver (Phase 1)
Gastroenteritis (Phase 4)
Gastrointestinal Microbiome (Phase 2)
Healthy Volunteers (Phase 3)
Hepatic Encephalopathy (Phase 3)
Hirschsprung Disease (Phase 2)
Inflammatory Bowel Diseases (Phase 3)
Intestinal Neoplasms (Phase 1)
Irritable Bowel Syndrome (Phase 4)
Klebsiella pneumoniae (Phase 1/Phase 2)
Lactation (Early Phase 1)
Liver Cirrhosis (Phase 2/Phase 3)
Metabolic Syndrome (Phase 4)
Mothers (Early Phase 1)
Non-alcoholic Fatty Liver Disease (Phase 2)
Osteoporosis (Phase 2)
Peritonitis (Phase 3)
Probiotics (Phase 4)
Purpura, Thrombocytopenic, Idiopathic (Phase 2)
Respiratory Tract Infections (Phase 4)
Rhinitis, Allergic (Phase 2)
Signs and Symptoms, Digestive (Phase 2)
| Trial | Phase | Start Date | Organizations | Indications |
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