l-serine Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Serine is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group, a carboxyl group, and a side chain consisting of a hydroxymethyl group, classifying it as a polar amino acid. It can be synthesized in the human body under normal physiological circumstances, making it a nonessential amino acid. It is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC.   Wikipedia

Chemistry

  • SMILES: N[C@@H](CO)C(=O)O
  • InChIKey: MTCFGRXMJLQNBG-REOHCLBHSA-N
  • Mol. Mass: 105.09
  • ALogP: -1.61
  • ChEMBL Molecule:
    serine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

(2s)-2-amino-3-hydroxypropanoic acid | beta-hydroxyalanine | beta-hydroxy-l-alanine | l-2-amino-3-hydroxypropionic acid | l-3-hydroxy-2-aminopropionic acid | l-3-hydroxy-alanine | l-ser | l-serin | l-serine | l-(-)-serine | l-(−)-serine | s | (s)-2-amino-3-hydroxypropanoic acid | (s)-alpha-amino-beta-hydroxypropionic acid | ser | serine | (s)-serine | (s)-(-)-serine | (s)-(−)-serine

Organizations (15)

Research & Development (15)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (6)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (6)


 

Alzheimer Disease (Phase 2)

Amyotrophic Lateral Sclerosis (Phase 2)

Hereditary Sensory and Autonomic Neuropathies (Phase 2)

Macula Lutea (Phase 2)

Non-alcoholic Fatty Liver Disease (Phase 1/Phase 2)

Vitamin B 6 Deficiency (Phase 2/Phase 3)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 13
  • # of Trial Organizations: 15

Trials by Phase

Trial Phase Start Date Organizations Indications

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