Related MeSH Hierarchy (5)
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Brain Diseases, Metabolic » Wernicke Encephalopathy
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Brain Diseases, Metabolic » Wernicke Encephalopathy
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Nutrition Disorders » Malnutrition » Deficiency Diseases » Avitaminosis » Vitamin B Deficiency » Thiamine Deficiency » Wernicke Encephalopathy
Diseases [C] » Chemically-Induced Disorders [C25] » Substance-Related Disorders » Alcohol-Related Disorders » Wernicke Encephalopathy
Psychiatry and Psychology [F] » Mental Disorders [F03] » Substance-Related Disorders » Alcohol-Related Disorders » Wernicke Encephalopathy
Description
An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. THIAMINE DEFICIENCY and chronic ALCOHOLISM are associated conditions. Pathologic features include periventricular petechial hemorrhages and neuropil breakdown in the diencephalon and brainstem. Chronic thiamine deficiency may lead to KORSAKOFF SYNDROME. (Adams et al., Principles of Neurology, 6th ed, pp1139-42; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp452-3) MeSH
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