Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Pathologic Processes » Inflammation » Systemic Inflammatory Response Syndrome
Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Pathologic Processes » Shock » Systemic Inflammatory Response Syndrome
Description
A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA <36 degrees C; (2) TACHYCARDIA >90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS. MeSH
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Subtype Terms (3)
Cytokine Release Syndrome
47 drugs (31 approved, 16 experimental)
Sepsis
314 drugs (194 approved, 120 experimental)
Shock, Septic
153 drugs (105 approved, 48 experimental)
Phase 3 Indicated Drugs (5)
Phase 2 Indicated Drugs (18)
Phase 1 Indicated Drugs (1)
Other Experimental Indicated Drugs (9)
Organization Involved with Phase 4 Indications (17)
Organization Involved with Phase 3 Indications (9)
Organization Involved with Phase 2 Indications (23)
Organization Involved with Phase 1 Indications (2)
Organization Involved with Other Experimental Indications (9)
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UMLS Data
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