Systemic Inflammatory Response Syndrome D018746

Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Pathologic Processes » Inflammation » Systemic Inflammatory Response Syndrome

Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Pathologic Processes » Shock » Systemic Inflammatory Response Syndrome

Description

A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA <36 degrees C; (2) TACHYCARDIA >90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.   MeSH

Subtype Terms (3)

Cytokine Release Syndrome
41 drugs (27 approved, 14 experimental)

Sepsis
296 drugs (178 approved, 118 experimental)

Shock, Septic
146 drugs (92 approved, 54 experimental)



Organization Involved with Phase 1 Indications (2)

Hierarchy Tree View

UMLS Data


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