Active Ingredient History
Thymoglobulin is an anti-human thymocyte immunoglobulin preparation made of purified polyclonal antibodies derived from rabbits. While these antibodies have a variety of specificities, their main mechanism of immunosuppression is through depletion of T cells. Thymoglobulin is currently approved for clinical use in Europe and the United States for renal allograft rejection, prevention of graft-vs.-host disease, and conditions involving bone marrow failure, including aplastic anemia and has additional off-label uses. Wikipedia
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Kidney Diseases (approved 1998)
Acne Vulgaris (Phase 3)
Adrenoleukodystrophy (Phase 2/Phase 3)
Allergy and Immunology (Phase 2/Phase 3)
Allogeneic Cells (Phase 2)
Allografts (Phase 2)
Anemia (Phase 4)
Anemia, Aplastic (Phase 4)
Anemia, Diamond-Blackfan (Phase 2/Phase 3)
Anemia, Hemolytic, Autoimmune (Phase 2/Phase 3)
Anemia, Sickle Cell (Phase 2/Phase 3)
Antilymphocyte Serum (Phase 2)
Autoimmune Diseases (Phase 2)
beta-Thalassemia (Phase 4)
Bone Marrow Cells (Phase 2)
Bone Marrow Failure Disorders (Phase 3)
Bone Marrow Transplantation (Phase 3)
Brain Injuries (Phase 2)
Brain Neoplasms (Phase 1)
Breast Neoplasms (Phase 2)
Bronchiectasis (Phase 3)
Burkitt Lymphoma (Phase 2)
Carcinoma, Hepatocellular (Phase 2)
Cerebellar Diseases (Phase 2)
Chediak-Higashi Syndrome (Phase 2)
Choroid Plexus Neoplasms (Phase 1)
Chronic Disease (Phase 2)
Crohn Disease (Phase 2)
Cystic Fibrosis (Phase 3)
Cystinosis (Phase 1/Phase 2)
Cytomegalovirus (Phase 4)
Cytomegalovirus Infections (Phase 4)
Desmoplastic Small Round Cell Tumor (Phase 2)
Diabetes Mellitus (Phase 4)
Diabetes Mellitus, Type 1 (Phase 3)
Diabetic Nephropathies (Phase 4)
DiGeorge Syndrome (Phase 1/Phase 2)
Drugs, Investigational (Phase 4)
Drug Therapy (Phase 4)
Dyskeratosis Congenita (Phase 2/Phase 3)
Encephalitis (Phase 2)
Ependymoma (Phase 1)
Epidermolysis Bullosa (Phase 2)
Fanconi Anemia (Phase 2)
Fucosidosis (Phase 2/Phase 3)
Gangliosidosis, GM1 (Phase 2/Phase 3)
Gaucher Disease (Phase 2/Phase 3)
Genetic Diseases, Inborn (Phase 2)
Glioma (Phase 1)
Glomerulonephritis (Phase 4)
Glomerulosclerosis, Focal Segmental (Phase 1/Phase 2)
Graft Rejection (Phase 4)
Graft vs Host Disease (Phase 4)
Hair (Phase 2)
Heart Transplantation (Phase 2)
Hematologic Diseases (Phase 2)
Hematologic Neoplasms (Phase 3)
Hematopoietic Stem Cell Transplantation (Phase 4)
Hemoglobinopathies (Phase 1)
Hemoglobinuria, Paroxysmal (Phase 2)
Histiocytosis, Langerhans-Cell (Phase 2)
Hodgkin Disease (Phase 3)
Hypoglycemia (Phase 1/Phase 2)
Idiopathic Pulmonary Fibrosis (Phase 3)
Immune System Diseases (Phase 2)
Immunologic Deficiency Syndromes (Phase 2)
Immunosuppression Therapy (Phase 4)
Infections (Phase 2)
Intestinal Neoplasms (Phase 2)
Kidney Diseases (Phase 4)
Kidney Failure, Chronic (Phase 4)
Kidney Neoplasms (Phase 2)
Kidney Transplantation (Phase 4)
Kidney Tubular Necrosis, Acute (Phase 1/Phase 2)
Lambert-Eaton Myasthenic Syndrome (Phase 2)
Leukemia (Phase 4)
Leukemia, Biphenotypic, Acute (Phase 2)
Leukemia, Large Granular Lymphocytic (Phase 2)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 2)
Leukemia, Lymphoid (Phase 3)
Leukemia-Lymphoma, Adult T-Cell (Phase 2)
Leukemia, Monocytic, Acute (Phase 2)
Leukemia, Myelogenous, Chronic, BCR-ABL Positive (Phase 2/Phase 3)
Leukemia, Myeloid (Phase 3)
Leukemia, Myeloid, Acute (Phase 4)
Leukemia, Myeloid, Chronic-Phase (Phase 2)
Leukemia, Myelomonocytic, Acute (Phase 2)
Leukemia, Myelomonocytic, Chronic (Phase 3)
Leukemia, Myelomonocytic, Juvenile (Phase 2)
Leukemia, Plasma Cell (Phase 2)
Leukemia, Prolymphocytic (Phase 2)
Leukemia, Prolymphocytic, T-Cell (Phase 1/Phase 2)
Leukodystrophy, Globoid Cell (Phase 2/Phase 3)
Leukodystrophy, Metachromatic (Phase 2/Phase 3)
Livedoid Vasculopathy (Phase 4)
Liver Diseases (Phase 4)
Liver Failure (Phase 2)
Liver Transplantation (Phase 4)
Living Donors (Phase 4)
Lung Diseases (Phase 3)
Lung Transplantation (Phase 3)
Lupus Erythematosus, Systemic (Phase 2)
Lymphohistiocytosis, Hemophagocytic (Phase 2)
Lymphoid Tissue (Phase 2/Phase 3)
Lymphoma (Phase 4)
Lymphoma, B-Cell (Phase 2)
Lymphoma, B-Cell, Marginal Zone (Phase 2)
Lymphoma, Follicular (Phase 2)
Lymphoma, Large B-Cell, Diffuse (Phase 2)
Lymphoma, Large-Cell, Anaplastic (Phase 2)
Lymphoma, Large-Cell, Immunoblastic (Phase 2)
Lymphoma, Mantle-Cell (Phase 2)
Lymphoma, Non-Hodgkin (Phase 3)
Lymphoma, T-Cell (Phase 2)
Lymphoma, T-Cell, Cutaneous (Phase 2)
Lymphoma, T-Cell, Peripheral (Phase 2)
Lymphomatoid Granulomatosis (Phase 2)
Lymphoproliferative Disorders (Phase 2)
Mannosidase Deficiency Diseases (Phase 2)
Medulloblastoma (Phase 1)
Melanoma (Phase 1/Phase 2)
Metabolic Diseases (Phase 2)
Mucopolysaccharidosis I (Phase 2)
Mucopolysaccharidosis VI (Phase 2)
Multiple Myeloma (Phase 4)
Multiple Sclerosis (Phase 2)
Multiple Sclerosis, Relapsing-Remitting (Phase 3)
Muscular Diseases (Phase 1)
Myasthenia Gravis (Phase 2)
Mycoses (Phase 2)
Myelodysplastic-Myeloproliferative Diseases (Phase 2/Phase 3)
Myelodysplastic Syndromes (Phase 4)
Myeloid Cells (Phase 1)
Myeloproliferative Disorders (Phase 3)
Neoplasm Metastasis (Phase 1/Phase 2)
Neoplasm, Residual (Phase 2)
Neoplasms (Phase 4)
Neoplasms, Germ Cell and Embryonal (Phase 1)
Neoplasms, Plasma Cell (Phase 2)
Nephritis (Phase 1/Phase 2)
Nerve Sheath Neoplasms (Phase 2)
Neural Tube Defects (Phase 2)
Neuroblastoma (Phase 2)
Neuroectodermal Tumors (Phase 1)
Neuroectodermal Tumors, Primitive (Phase 1)
Neuromyelitis Optica (Phase 2/Phase 3)
Neuronal Ceroid-Lipofuscinoses (Phase 2/Phase 3)
Neutropenia (Phase 2/Phase 3)
Niemann-Pick Diseases (Phase 2/Phase 3)
Opsoclonus-Myoclonus Syndrome (Phase 2)
Organ Preservation Solutions (Phase 4)
Organ Transplantation (Phase 4)
Ovarian Neoplasms (Phase 2)
Ovulation Induction (Phase 4)
Pancytopenia (Phase 2)
Pediatrics (Phase 1)
Plasmacytoma (Phase 2)
Precancerous Conditions (Phase 2)
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (Phase 1/Phase 2)
Primary Immunodeficiency Diseases (Phase 2)
Primary Myelofibrosis (Phase 2/Phase 3)
Pulmonary Disease, Chronic Obstructive (Phase 3)
Rabies (Phase 1/Phase 2)
Recurrence (Phase 3)
Renal Insufficiency (Phase 4)
Reperfusion Injury (Phase 4)
Rhabdoid Tumor (Phase 1)
Rhabdomyosarcoma (Phase 2)
Sandhoff Disease (Phase 2/Phase 3)
Sarcoma (Phase 2)
Sarcoma, Ewing (Phase 2)
Sarcoma, Myeloid (Phase 2)
Scleroderma, Systemic (Phase 3)
Severe Combined Immunodeficiency (Phase 1/Phase 2)
Sezary Syndrome (Phase 2)
Shwachman-Diamond Syndrome (Phase 2/Phase 3)
Stem Cell Transplantation (Phase 3)
Stiff-Person Syndrome (Phase 2)
Tay-Sachs Disease (Phase 2/Phase 3)
Thalassemia (Phase 2/Phase 3)
Thrombocytopenia (Phase 2)
Thymoma (Phase 2)
Thyroid Neoplasms (Phase 1/Phase 2)
Transplantation (Phase 4)
Transplantation, Autologous (Phase 2)
Transplantation, Homologous (Phase 2)
Vascular Grafting (Phase 3)
Vasculitis (Phase 1)
Vasculitis, Central Nervous System (Phase 2)
Virus Diseases (Phase 2/Phase 3)
Waldenstrom Macroglobulinemia (Phase 2)
Wiskott-Aldrich Syndrome (Phase 1/Phase 2)
Wolman Disease (Phase 2/Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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