Related MeSH Hierarchy (6)
Diseases [C] » Neoplasms [C04] » Neoplasms by Site » Nervous System Neoplasms » Paraneoplastic Syndromes, Nervous System » Myasthenia Gravis
Diseases [C] » Neoplasms [C04] » Paraneoplastic Syndromes » Paraneoplastic Syndromes, Nervous System » Myasthenia Gravis
Diseases [C] » Nervous System Diseases [C10] » Autoimmune Diseases of the Nervous System » Myasthenia Gravis
Diseases [C] » Nervous System Diseases [C10] » Neurodegenerative Diseases » Paraneoplastic Syndromes, Nervous System » Myasthenia Gravis
Diseases [C] » Nervous System Diseases [C10] » Neuromuscular Diseases » Neuromuscular Junction Diseases » Myasthenia Gravis
Diseases [C] » Immune System Diseases [C20] » Autoimmune Diseases » Autoimmune Diseases of the Nervous System » Myasthenia Gravis
Description
A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition. MeSH
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Subtype Terms (3)
Lambert-Eaton Myasthenic Syndrome
10 drugs (8 approved, 2 experimental)
Phase 4 Indicated Drugs (3)
Phase 3 Indicated Drugs (17)
Phase 2 Indicated Drugs (18)
Phase 1 Indicated Drugs (7)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 4 Indications (4)
Organization Involved with Phase 3 Indications (28)
Organization Involved with Phase 2 Indications (22)
Organization Involved with Phase 1 Indications (6)
Organization Involved with Other Experimental Indications (4)
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UMLS Data
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