Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Connective and Soft Tissue » Neoplasms, Muscle Tissue » Myosarcoma » Rhabdomyosarcoma
Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Connective and Soft Tissue » Sarcoma » Myosarcoma » Rhabdomyosarcoma
Description
A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9) MeSH
Hierarchy View
Subtype Terms (2)
Rhabdomyosarcoma, Alveolar
11 drugs (7 approved, 4 experimental)
Rhabdomyosarcoma, Embryonal
11 drugs (7 approved, 4 experimental)
Approved Indicated Drugs (1)
Phase 4 Indicated Drugs (3)
Phase 1 Indicated Drugs (38)
Other Experimental Indicated Drugs (4)
Organization Involved with Phase 4 Indications (1)
Organization Involved with Phase 3 Indications (22)
Children's Cancer and Leukaemia Group
Cooperative Weichteilsarkom Study Group
Gesellschaft fur Padiatrische Onkologie und Hamatologie - Austria
Gesellschaft fur Padiatrische Onkologie und Hamatologie - Germany
Organization Involved with Phase 2 Indications (57)
Centre Ocsar Lambet, Lille, France
Eastern Cooperative Oncology Group
Icahn School of Medicine at Mount Sinai
Japan Rhabdomyosarcoma Study Group
Katholieke Universiteit Leuven
KK Women's and Children's Hospital
Kyoto Prefectural University of Medicine
Maria Sklodowska Curie Children's Hospital
Memorial Sloan-Kettering Cancer Center
National Center for Child Health and Development, Japan
National Hospital Organisation Nagoya Medical Centre
National Institutes of Health (NIH)
Neuroblastoma and Medulloblastoma Translational Research Consortium
Oregon Health and Science University
Royal Liverpool & Broadgreen University Hospitals NHS Truts
Royal Marsden Hospital NHS Trust
Saitama Children's Medical Center
Sarcoma Alliance for Research through Collaboration
Societe Francaise Oncologie Pediatrique
Organization Involved with Phase 1 Indications (28)
Organization Involved with Other Experimental Indications (2)
Hierarchy Tree View
UMLS Data
YOU AGREE THAT THE INFORMATION PROVIDED ON THIS WEBSITE IS PROVIDED “AS IS”, WITHOUT ANY WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE, OR NON-INFRINGEMENT OF ANY THIRD-PARTY PATENT, COPYRIGHT, OR ANY OTHER THIRD-PARTY RIGHT. IN NO EVENT SHALL THE CREATORS OF THE WEBSITE OR WASHINGTON UNIVERSITY BE LIABLE FOR ANY DIRECT, INDIRECT, SPECIAL, OR CONSEQUENTIAL DAMAGES ARISING OUT OF OR IN ANY WAY CONNECTED WITH THE WEBSITE, THE USE OF THE WEBSITE, OR THIS AGREEMENT, WHETHER IN BREACH OF CONTRACT, TORT OR OTHERWISE, EVEN IF SUCH PARTY IS ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.