Diseases [C] » Skin and Connective Tissue Diseases [C17] » Connective Tissue Diseases » Scleroderma, Systemic
Diseases [C] » Skin and Connective Tissue Diseases [C17] » Skin Diseases » Scleroderma, Systemic
Description
A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA. MeSH
Hierarchy View
Subtype Terms (2)
Scleroderma, Diffuse
36 drugs (21 approved, 15 experimental)
Scleroderma, Limited
2 drugs (1 approved, 1 experimental)
Phase 4 Indicated Drugs (12)
Phase 1 Indicated Drugs (17)
Other Experimental Indicated Drugs (15)
Organization Involved with Phase 4 Indications (22)
A.O. Ospedale Maggiore di Lodi
Federal University of Sao Paulo
Instituto Mexicano del Seguro Social
Mastelli srl, via Bussana Vecchia, Sanremo, Italy
Organization Involved with Phase 3 Indications (51)
Institute of Post Graduate Medical Education & Research
Japan Agency for Medical Research and Development
Medical University of South Carolina
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)
Presbyterian/St. Luke's Medical Center, Denver
Sanjay Gandhi Postgraduate Institute of Medical Sciences
University of California, San Diego
Organization Involved with Phase 2 Indications (83)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Rainier Clinical Research Center
Rudolph Rupert Scleroderma Program
Salford Royal Foundation NHS Trust
Scleroderma Research Consultants LLC
South-Eastern Norway Regional Health Authority
Organization Involved with Phase 1 Indications (18)
Organization Involved with Other Experimental Indications (11)
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UMLS Data
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