Neural Tube Defects D009436

Description

Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)   MeSH

Subtype Terms (7)

Anencephaly
 

Arnold-Chiari Malformation
2 approved drugs

Encephalocele
2 approved drugs

Meningocele
 

Meningomyelocele
4 drugs (2 approved, 2 experimental)

Pentalogy of Cantrell
 

Spinal Dysraphism
6 approved drugs


Phase 1 Indicated Drugs (1)

Other Experimental Indicated Drugs (3)


Organization Involved with Phase 3 Indications (2)

Organization Involved with Phase 2 Indications (2)

Organization Involved with Phase 1 Indications (2)

Hierarchy Tree View

UMLS Data


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