Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Leukemia » Leukemia, Lymphoid » Leukemia, T-Cell » Leukemia, Large Granular Lymphocytic
Diseases [C] » Hemic and Lymphatic Diseases [C15] » Lymphatic Diseases » Lymphoproliferative Disorders » Leukemia, Lymphoid » Leukemia, T-Cell » Leukemia, Large Granular Lymphocytic
Diseases [C] » Immune System Diseases [C20] » Immunoproliferative Disorders » Lymphoproliferative Disorders » Leukemia, Lymphoid » Leukemia, T-Cell » Leukemia, Large Granular Lymphocytic
Description
A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease. MeSH
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Phase 1 Indicated Drugs (20)
Organization Involved with Phase 3 Indications (9)
Organization Involved with Phase 2 Indications (20)
Organization Involved with Phase 1 Indications (10)
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UMLS Data
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