Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464

Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Pathologic Processes » Disease Attributes » Chronic Disease » Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Leukemia » Leukemia, Myeloid » Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Diseases [C] » Hemic and Lymphatic Diseases [C15] » Hematologic Diseases » Bone Marrow Diseases » Myeloproliferative Disorders » Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Description

Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.   MeSH

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Subtype Terms (3)

Blast Crisis
9 drugs (7 approved, 2 experimental)

Leukemia, Myeloid, Accelerated Phase
11 drugs (9 approved, 2 experimental)

Leukemia, Myeloid, Chronic-Phase
169 drugs (103 approved, 66 experimental)


Phase 4 Indicated Drugs (1)

Phase 2 Indicated Drugs (92)


Organization Involved with Phase 3 Indications (72)

Organization Involved with Phase 2 Indications (216)

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UMLS Data


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