Active Ingredient History

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Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Experimental data suggest that amlodipine binds to both dihydropyridine and nondihydropyridine binding sites. The contractile processes of cardiac muscle and vascular smooth muscle are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Amlodipine inhibits calcium ion influx across cell membranes selectively, with a greater effect on vascular mooth muscle cells than on cardiac muscle cells. Amlodipine is indicated for the treatment of hypertension and coronary artery disease.   NCATS

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Drug Pricing (per unit)

United States

$0.0116 - $9.3847

Australia

$0.0320 - $0.3303
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

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( amlodipine (norvasc), olmesartan (benicar) - other name: amlodipine and olmesartan medoxomil )
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( amlodipine (norvasc), olmesartan (benicar), hydrochlorothiazide (esidrix) - other name: olmesartan medoxomil, amlodipine and hydrochlorothiazide )
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( amlodipine (norvasc), telmisartan (micardis) - other names: fixed dose combination pill of telmisartan 40mg and amlodipine 5 mg, telmisartan and amlodipine )
3-ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate | 3-ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate | aliskiren / amlodipine | aliskiren / amlodipine / hydrochlorothiazide | amlodipine | amlodipine (as besylate) / valsartan | amlodipine/atorvastatin | amlodipine besilate | amlodipine besilate / valsartan | amlodipine besylate | amlodipine besylate / valsartan / hydrochlorothiazide | amlodipine camsylate | amlodipine free base | amlodipine maleate | amlodipine mesilate | amlodipine mesylate | amlodipine mixture with valsartan | amlodipine orotate | amlodipine / valsartan | amlodipine / valsartan / hydrochlorothiazide | amlodipino | amlodipinum | amlopidine | amlopres | amvaz | astudal 5 | hgp0904 | istin | norvas | norvasc | racemic amlodipine | (rs)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate | telmisartan / amlodipine | telmisartan /amlodipine besilate | uk-4834011 | uk-48340-11 | uk-4834026 | uk-48340-26

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