Diseases [C] » Respiratory Tract Diseases [C08] » Respiration Disorders » Apnea » Sleep Apnea Syndromes » Sleep Apnea, Obstructive
Diseases [C] » Nervous System Diseases [C10] » Sleep Wake Disorders » Dyssomnias » Sleep Disorders, Intrinsic » Sleep Apnea Syndromes » Sleep Apnea, Obstructive
Description
A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395) MeSH
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Subtype Terms (1)
Obesity Hypoventilation Syndrome
2 drugs (1 approved, 1 experimental)
Approved Indicated Drugs (3)
Phase 4 Indicated Drugs (56)
Phase 2 Indicated Drugs (36)
Phase 1 Indicated Drugs (8)
Other Experimental Indicated Drugs (22)
Organization Involved with Phase 4 Indications (48)
Ankara Yildirim Beyazıt University
Associação Fundo de Incentivo à Pesquisa
Associacao Fundo de Incentivo a Psicofarmcologia
Federal University of Rio Grande do Sul
Institut National de la Santé Et de la Recherche Médicale, France
Katholieke Universiteit Leuven
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health (NIH)
Organization Involved with Phase 3 Indications (22)
Organization Involved with Phase 2 Indications (37)
American Academy of Otolaryngology-Head and Neck Surgery Foundation
Centre de Recherche en Nutrition Humaine Rhone-Alpe
Medical University of South Carolina
Mid-Atlantic Epilepsy and Sleep Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Organization Involved with Phase 1 Indications (15)
Organization Involved with Other Experimental Indications (21)
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UMLS Data
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