Active Ingredient History
Mrtoprolol is a beta-adrenergic receptor blocking agent. In vitro and in vivo animal studies have shown that it has a preferential effect on beta-1 adrenoreceptors, chiefly located in cardiac muscle. Clinical pharmacology studies have confirmed the beta-blocking activity of metoprolol in man, as shown by (1) reduction in heart rate and cardiac output at rest and upon exercise, (2) reduction of systolic blood pressure upon exercise, (3) inhibition of isoproterenol-induced tachycardia, and (4) reduction of reflex orthostatic tachycardia. Mrtoprolol is indicated for the treatment of hypertension, angina pectoris and myocardial infarction NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Combination drugs
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Acute Coronary Syndrome (Phase 4)
Adrenergic beta-Antagonists (Phase 4)
Aged (Phase 2)
Aging (Phase 2)
Anesthesia and Analgesia (Phase 4)
Angina Pectoris (Phase 4)
Angina, Stable (Early Phase 1)
Angina, Unstable (Phase 4)
Anterior Wall Myocardial Infarction (Phase 2)
Aortic Valve Insufficiency (Phase 4)
Aortic Valve Stenosis (Phase 2)
Arrhythmias, Cardiac (Phase 4)
Asthma (Phase 4)
Atherosclerosis (Phase 3)
Atrial Fibrillation (Phase 4)
Atrial Flutter (Phase 4)
Bariatric Surgery (Phase 4)
beta-Thalassemia (Phase 2/Phase 3)
Blood Pressure (Phase 4)
Breast Neoplasms (Phase 3)
Cardiomyopathies (Phase 4)
Cardiomyopathy, Dilated (Phase 4)
Cardiomyopathy, Hypertrophic (Phase 4)
Cognitive Dysfunction (Phase 2)
Coronary Artery Disease (Phase 4)
Coronary Disease (Phase 4)
COVID-19 (Early Phase 1)
Death, Sudden, Cardiac (Phase 2)
Dermatitis, Atopic (Phase 1)
Diabetes Mellitus (Phase 4)
Diabetes Mellitus, Type 2 (Phase 4)
Diagnosis (Phase 2)
Drug Overdose (Phase 4)
Drugs, Investigational (Phase 4)
Dyspnea (Early Phase 1)
Endothelium (Phase 4)
Essential Hypertension (Phase 4)
Fasting (Phase 1)
Fibrosis (Phase 3)
Foramen Ovale, Patent (Phase 4)
Gastric Bypass (Phase 4)
Graves Disease (Phase 4)
Healthy Volunteers (Phase 1)
Heart (Phase 4)
Heart Arrest (Phase 2)
Heart Diseases (Phase 4)
Heart Failure (Phase 4)
Heart Failure, Diastolic (Phase 4)
Heart Failure, Systolic (Phase 4)
Heart Rate (Phase 4)
Heart Valve Diseases (Phase 4)
Hematologic Neoplasms (Phase 1/Phase 2)
HIV Infections (Phase 1)
Hypercholesterolemia (Phase 3)
Hypertension (Phase 4)
Hypertrophy, Left Ventricular (Phase 4)
Infant, Premature (Phase 2)
Ischemic Stroke (Phase 3)
Kidney Failure, Chronic (Phase 3)
Lung Neoplasms (Phase 3)
Macular Edema (Phase 1/Phase 2)
Malaria (Phase 1)
Medicine, Chinese Traditional (Phase 4)
Metabolic Detoxication, Phase I (Phase 1)
Metabolic Syndrome (Phase 4)
Metoprolol (Phase 4)
Migraine Disorders (Phase 4)
Mitral Valve Insufficiency (Phase 2/Phase 3)
Mitral Valve Prolapse (Phase 3)
Multiple Trauma (Phase 2)
Muscular Dystrophy, Duchenne (Phase 3)
Myocardial Infarction (Phase 4)
Myocardial Stunning (Phase 4)
Nasal Polyps (Phase 4)
Neoplasms (Phase 1/Phase 2)
Non-ST Elevated Myocardial Infarction (Phase 4)
Obesity (Phase 4)
Osteoarthritis (Phase 4)
Percutaneous Coronary Intervention (Phase 4)
Peripheral Arterial Disease (Phase 3)
Pharmacokinetics (Phase 1)
Pharmacology (Phase 1)
Plasma (Early Phase 1)
Polycystic Kidney Diseases (Phase 3)
Prader-Willi Syndrome (Phase 2)
Prehypertension (Phase 4)
Psoriasis (Phase 1)
Pulmonary Disease, Chronic Obstructive (Phase 4)
Recurrence (Phase 2/Phase 3)
Renal Dialysis (Phase 4)
Renal Insufficiency, Chronic (Phase 3)
Respiratory Distress Syndrome (Phase 3)
Sclerosis (Phase 3)
Sexual Dysfunction, Physiological (Phase 4)
Sleep Apnea Syndromes (Phase 2/Phase 3)
Sports Medicine (Phase 1)
ST Elevation Myocardial Infarction (Phase 4)
Syncope, Vasovagal (Phase 4)
Tachycardia (Phase 3)
Tachycardia, Ventricular (Phase 2)
Takotsubo Cardiomyopathy (Phase 1/Phase 2)
Thoracic Surgery (Phase 4)
Tuberculosis (Phase 4)
Vaccines (Phase 4)
Vascular Diseases (Phase 4)
Ventricular Dysfunction, Left (Phase 4)
Ventricular Fibrillation (Phase 2)
Ventricular Premature Complexes (Phase 4)
Virus Diseases (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
Feedback
Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).
Report issue
