Congenital Hyperinsulinism D044903

Related MeSH Hierarchy (4)

Diseases [C] » Digestive System Diseases [C06] » Pancreatic Diseases » Congenital Hyperinsulinism

Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Glucose Metabolism Disorders » Hyperinsulinism » Congenital Hyperinsulinism

Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Glucose Metabolism Disorders » Hypoglycemia » Congenital Hyperinsulinism

Description

A familial, nontransient HYPOGLYCEMIA with defects in negative feedback of GLUCOSE-regulated INSULIN release. Clinical phenotypes include HYPOGLYCEMIA; HYPERINSULINEMIA; SEIZURES; COMA; and often large BIRTH WEIGHT. Several sub-types exist with the most common, type 1, associated with mutations on an ATP-BINDING CASSETTE TRANSPORTERS (subfamily C, member 8).   MeSH

Hierarchy View

Subtype Terms (1)

Nesidioblastosis
1 experimental drug


Phase 4 Indicated Drugs (1)

Phase 3 Indicated Drugs (3)

Phase 1 Indicated Drugs (1)


Organization Involved with Phase 4 Indications (1)

Organization Involved with Phase 3 Indications (4)

Organization Involved with Phase 1 Indications (2)

Organization Involved with Other Experimental Indications (1)

Hierarchy Tree View

UMLS Data


YOU AGREE THAT THE INFORMATION PROVIDED ON THIS WEBSITE IS PROVIDED “AS IS”, WITHOUT ANY WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE, OR NON-INFRINGEMENT OF ANY THIRD-PARTY PATENT, COPYRIGHT, OR ANY OTHER THIRD-PARTY RIGHT. IN NO EVENT SHALL THE CREATORS OF THE WEBSITE OR WASHINGTON UNIVERSITY BE LIABLE FOR ANY DIRECT, INDIRECT, SPECIAL, OR CONSEQUENTIAL DAMAGES ARISING OUT OF OR IN ANY WAY CONNECTED WITH THE WEBSITE, THE USE OF THE WEBSITE, OR THIS AGREEMENT, WHETHER IN BREACH OF CONTRACT, TORT OR OTHERWISE, EVEN IF SUCH PARTY IS ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.