Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Signs and Symptoms » Neurologic Manifestations » Neuromuscular Manifestations » Muscle Hypertonia » Muscle Spasticity
Diseases [C] » Musculoskeletal Diseases [C05] » Muscular Diseases » Muscle Spasticity
Diseases [C] » Nervous System Diseases [C10] » Neurologic Manifestations » Neuromuscular Manifestations » Muscle Hypertonia » Muscle Spasticity
Description
A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a "free interval") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54) MeSH
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Approved Indicated Drugs (5)
Phase 3 Indicated Drugs (4)
Other Experimental Indicated Drugs (4)
Organization Involved with Phase 4 Indications (35)
Organization Involved with Phase 3 Indications (46)
Institut fur Klinische Forschung, Germany
Neurology Center of New England P.C.
People's Liberation Army of China
Organization Involved with Phase 2 Indications (40)
Hamilton Health Sciences Corporation
Health Sciences Centre Foundation, Manitoba
Hoosier Cancer Research Network
Hormozgan University of Medical Sciences
Institut National de la Santé Et de la Recherche Médicale, France
Organization Involved with Phase 1 Indications (11)
Organization Involved with Other Experimental Indications (14)
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UMLS Data
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