Related MeSH Hierarchy (4)
Diseases [C] » Nervous System Diseases [C10] » Neurocutaneous Syndromes » von Hippel-Lindau Disease
Diseases [C] » Cardiovascular Diseases [C14] » Vascular Diseases » Angiomatosis » von Hippel-Lindau Disease
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Congenital Abnormalities » Abnormalities, Multiple » Ciliopathies » von Hippel-Lindau Disease
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Ciliopathies » von Hippel-Lindau Disease
Description
An autosomal dominant disorder caused by mutations in a tumor suppressor gene. This syndrome is characterized by abnormal growth of small blood vessels leading to a host of neoplasms. They include HEMANGIOBLASTOMA in the RETINA; CEREBELLUM; and SPINAL CORD; PHEOCHROMOCYTOMA; pancreatic tumors; and renal cell carcinoma (see CARCINOMA, RENAL CELL). Common clinical signs include HYPERTENSION and neurological dysfunctions. MeSH
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Approved Indicated Drugs (1)
Phase 1 Indicated Drugs (3)
Other Experimental Indicated Drugs (2)
Organization Involved with Phase 2 Indications (14)
Organization Involved with Phase 1 Indications (2)
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