Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Metalloproteases » Metalloendopeptidases » ADAM Proteins » ADAMTS Proteins
Chemicals and Drugs [D] » Carbohydrates [D09] » Glycoconjugates » Glycoproteins » ADAM Proteins » ADAMTS Proteins
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » ADAM Proteins » ADAMTS Proteins
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Scleroproteins » Extracellular Matrix Proteins » ADAMTS Proteins
Description
A subfamily of ADAM proteases that are distinguished by the presence of one or more THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand motifs that contain characteristic TRYPTOPHAN, ARGININE, and CYSTEINE residues respectively. In contrast to ADAM proteins, which reside on CELL MEMBRANES, ADAMTS proteases are secreted and function in the EXTRACELLULAR MATRIX. MeSH
Hierarchy View
Subtype Terms (6)
Hierarchy Tree View
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