Trial | NCT03585140  Report issue

Title

Low Glycemic Index and Load Diet for the Treatment of Acne
Effect of Adding a Diet With Low Glycemic Index and Load During 12 Weeks for the Treatment of Moderate Acne in Adults: a Randomized Clinical Trial

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    52
Clinical trial to determine the effect of adding a diet with low glycemic index and load to adults for the treatment of moderate acne. Adult patients with acne where recruited in two groups, A and B. Group A received a normal diet according to their metabolic status and group B received a diet with low glycemic index and load. Outcomes were measured at week 12.
Clinical trial to determine the effect of adding a diet with low glycemic index and load to adults for the treatment of moderate acne. Adult patients with acne where recruited in two groups, A and B. Both groups of treatment were treated with doxycycline 100 mg per day plus adapalene 0.1% gel daily for 12 weeks. During pharmacologic treatment, all patients had nutrition counseling monthly. Group A received a normal diet according to their metabolic status and group B received a diet with low glycemic index and load. At the end of the trial, the change in acne lesions count was analyzed and also their metabolic status. Quality of life was also measured.
Study Started
Jan 01
2016
Primary Completion
May 01
2016
Study Completion
Nov 30
2016
Last Update
Jul 16
2018

Other Normal diet

The energy consumption of each of the participants will be calculated, using the Mifflin-St Jeor formula. Each participant will receive a standard menu of 6 days according to their metabolic requirements and a list of equivalent foods. The distribution of macronutrients will be: 45% carbohydrates, 30% lipids and 25% proteins.

Other Low glycemic diet

The energy consumption of each of the participants will be calculated, using the Mifflin-St Jeor formula. Each participant will receive a standard menu of 6 days according to their metabolic requirements and a list of equivalent foods. A list of foods classified as having low index and glycemic load was used according to the mexican equivalent food system. The distribution of macronutrients will be: 45% carbohydrates, 30% lipids and 25% proteins. Milk and vitamin supplements will be eliminated from the diet.

Drug Adapalene 0.1% Gel

Adapalene 0.1% gel daily at night for 12 weeks, applied on the face, chest and back.

  • Other names: Adapalene

Drug Doxycycline

Doxycycline 100 mg per day orally, before breakfast

Normal Diet Active Comparator

Participants will receive a normal diet according to their metabolic status.

Low glycemic diet Experimental

Participants will receive a low-glycemic index and load diet according to their metabolic status. Milk and vitamin supplements will be eliminated from the diet.

Criteria 

Inclusion Criteria:

Having moderate inflammatory acne
18 to 25 years old
Male
Stable weight during the last 3 months

Exclusion Criteria:

Previous or actual isotretinoin therapy
Antibiotic therapy or during the last 3 months
Therapy based on peelings, dermabrasion, laser or intense pulsed light during the last 6 months
Endocrine disorders
Drug and alcohol consumption during the last 6 months
Tabacco use during the last 6 months
Lactose intolerance
Have eating disorders or gastrointestinal disorders
Actual nutrition therapy
Have chronic diseases that requires pharmacologic therapy
Severe acne that requires isotretinoin therapy
No Results Posted