Trial | NCT00599430  Report issue

Title

Evaluation of Probiotics on Symptoms of Upper Respiratory Tract Infections
Probiotics and Effects on Illness-Related Symptoms for Pre-School Age Children

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    326
The aim of the present prospective study is to investigate whether the consumption of certain probiotic strains over a six-month winter/spring season would be able to affect the incidence and duration of upper respiratory tract infections, in otherwise healthy children as well as determining whether a combination of two strains would perform differently from a single strain version.
Study Started
Nov 30
2005
Primary Completion
May 31
2006
Study Completion
May 31
2006
Last Update
Jan 23
2008
Estimate

Dietary Supplement Placebo

Inert excipient

Dietary Supplement Lactobacillus acidophilus NCFM

1e10 CFU/day

Dietary Supplement Combination of Lactobacillus acidophilus and Bifidobacterium lactis

1x10e10 CFU/day

1 Placebo Comparator

Placebo

Active 1 Active Comparator

One probiotic strain

Active 2 Active Comparator

Blend of two strains

Criteria 

Inclusion Criteria:

Children aged 3-5 years of normal nutritional status and health

Exclusion Criteria:

Contraindications to dairy products (lactose intolerance or cow's milk allergy)
Indicators of inflammatory disease, intestinal disease, Crohn's disease, colitis, celiac disease
Chronic cough from recurring respiratory distress-related diseases
Hirschsprung's disease
Cystic fibrosis
Other metabolic, neurological, or anatomic alteration that predisposes participation
Intake of probiotics within the last 3 weeks
No Results Posted