Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Pathologic Processes » Protein Aggregation, Pathological
Phenomena and Processes [G] » Chemical Phenomena [G02] » Biochemical Phenomena » Protein Aggregation, Pathological
Description
A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS. MeSH
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