Related MeSH Hierarchy (7)
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Dementia » Huntington Disease
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Movement Disorders » Dyskinesias » Chorea » Huntington Disease
Diseases [C] » Nervous System Diseases [C10] » Neurodegenerative Diseases » Heredodegenerative Disorders, Nervous System » Huntington Disease
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Heredodegenerative Disorders, Nervous System » Huntington Disease
Psychiatry and Psychology [F] » Mental Disorders [F03] » Neurocognitive Disorders » Cognition Disorders » Huntington Disease
Psychiatry and Psychology [F] » Mental Disorders [F03] » Neurocognitive Disorders » Dementia » Huntington Disease
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Basal Ganglia Diseases » Huntington Disease
Description
A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4) MeSH
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Approved Indicated Drugs (2)
Phase 4 Indicated Drugs (1)
Phase 2 Indicated Drugs (30)
Other Experimental Indicated Drugs (8)
Organization Involved with Phase 4 Indications (5)
Organization Involved with Phase 3 Indications (23)
Organization Involved with Phase 2 Indications (38)
Organization Involved with Phase 1 Indications (18)
Organization Involved with Other Experimental Indications (1)
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UMLS Data
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