Diseases [C] » Digestive System Diseases [C06] » Gastrointestinal Diseases » Esophageal Diseases » Deglutition Disorders » Esophageal Motility Disorders
Description
Disorders affecting the motor function of the UPPER ESOPHAGEAL SPHINCTER; LOWER ESOPHAGEAL SPHINCTER; the ESOPHAGUS body, or a combination of these parts. The failure of the sphincters to maintain a tonic pressure may result in gastric reflux of food and acid into the esophagus (GASTROESOPHAGEAL REFLUX). Other disorders include hypermotility (spastic disorders) and markedly increased amplitude in contraction (nutcracker esophagus). MeSH
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Subtype Terms (5)
CREST Syndrome
2 drugs (1 approved, 1 experimental)
Esophageal Achalasia
20 drugs (15 approved, 5 experimental)
Esophageal Spasm, Diffuse
2 approved drugs
Gastroesophageal Reflux
144 drugs (57 approved, 87 experimental)
Phase 4 Indicated Drugs (4)
Phase 2 Indicated Drugs (3)
Phase 1 Indicated Drugs (1)
Organization Involved with Phase 4 Indications (1)
Organization Involved with Phase 2 Indications (4)
Organization Involved with Phase 1 Indications (1)
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UMLS Data
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