Mastocytosis D008415

Description

A rare neoplastic disorder characterized by a clonal proliferation of MAST CELLS, associated with KIT-D816 mutations, and accompanied by aberrant mast cell activation. The abnormal increase of MAST CELLS may occur in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA).   MeSH

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Subtype Terms (4)

Mastocytosis, Cutaneous
4 drugs (3 approved, 1 experimental)

Mastocytosis, Systemic
26 drugs (18 approved, 8 experimental)


Approved Indicated Drugs (1)

Phase 1 Indicated Drugs (2)

Other Experimental Indicated Drugs (1)


Organization Involved with Phase 1 Indications (2)

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UMLS Data


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