Active Ingredient History
Mycophenolic acid (MPA) possesses antibacterial, antifungal, antiviral, immunosuppressive and anticancer properties. Mycophenolic acid (MPA) is a fungal metabolite that was initially discovered by Bartolomeo Gosio in 1893 as an antibiotic against anthrax bacillus, Bacillus anthracis. It is an uncompetitive and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH), and therefore inhibits the de novo pathway of guanosine nucleotide synthesis without incorporation to DNA. It was approved under the brand name Myfortic for the prophylaxis of organ rejection in adult patients receiving a kidney transplant and is indicated for the prophylaxis of organ rejection in pediatric patients 5 years of age and older who are at least 6 months post kidney transplant. Myfortic is to be used in combination with cyclosporine and corticosteroids. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Abdominal Wall (Early Phase 1)
Acne Vulgaris (Phase 3)
Adenosine Deaminase (Phase 1)
Adrenoleukodystrophy (Phase 2)
Allogeneic Cells (Phase 2)
Allografts (Phase 4)
alpha-Mannosidosis (Phase 2)
Alveolitis, Extrinsic Allergic (Phase 4)
Amyotrophic Lateral Sclerosis (Phase 2)
Anemia (Phase 2)
Anemia, Aplastic (Phase 2)
Anemia, Diamond-Blackfan (Phase 2)
Anemia, Hemolytic, Autoimmune (Phase 3)
Anemia, Refractory (Phase 2)
Anemia, Sickle Cell (Phase 2)
Antigens, CD (Phase 1)
Arthritis, Juvenile (Phase 2)
Arthritis, Rheumatoid (Phase 2)
Aspartylglucosaminuria (Phase 2)
Astrocytoma (Phase 1)
Atherosclerosis (Phase 4)
Autoimmune Diseases (Phase 3)
beta-Thalassemia (Phase 4)
BK Virus (Phase 4)
Bone Marrow Cells (Phase 2)
Bone Marrow Failure Disorders (Phase 2)
Bone Marrow Transplantation (Phase 3)
Brain Neoplasms (Phase 1)
Breast Neoplasms (Phase 1/Phase 2)
Burkitt Lymphoma (Phase 2)
Carcinoma, Hepatocellular (Phase 4)
Carcinoma, Renal Cell (Phase 1/Phase 2)
Cardiomyopathies (Phase 3)
Cardiomyopathy, Dilated (Phase 3)
Cardiovascular Diseases (Phase 4)
Cerebellum (Phase 2)
Chediak-Higashi Syndrome (Phase 2)
Chemical and Drug Induced Liver Injury (Phase 2)
Choroid Plexus Neoplasms (Phase 1)
Chromosome Aberrations (Phase 2)
Chronic Disease (Phase 2)
Churg-Strauss Syndrome (Phase 4)
Common Variable Immunodeficiency (Phase 2)
Conjunctivitis (Phase 2)
Corneal Diseases (Phase 2/Phase 3)
Corneal Transplantation (Phase 4)
COVID-19 (Phase 4)
Crohn Disease (Phase 2)
Cyclophosphamide (Phase 4)
Cystitis, Interstitial (Phase 3)
Cytomegalovirus Infections (Phase 4)
Death, Sudden, Cardiac (Phase 3)
Deficiency Diseases (Phase 2)
Delayed Graft Function (Phase 4)
Dermatitis, Atopic (Phase 4)
Dermatology (Phase 2)
Dermatomyositis (Phase 2)
Desmoplastic Small Round Cell Tumor (Phase 2)
Diabetes Mellitus, Type 1 (Phase 4)
Diabetic Nephropathies (Phase 3)
DiGeorge Syndrome (Phase 1/Phase 2)
Diploidy (Phase 2)
Drug Evaluation (Phase 4)
Drug Interactions (Phase 4)
Dry Eye Syndromes (Phase 2)
Dyskeratosis Congenita (Phase 2)
End Stage Liver Disease (Phase 4)
Ependymoma (Phase 1)
Epidermolysis Bullosa (Phase 2)
Everolimus (Phase 2/Phase 3)
Fanconi Anemia (Phase 2/Phase 3)
Fasting (Phase 1)
Fucosidosis (Phase 2)
Gangliosidosis, GM1 (Phase 2)
Gastrointestinal Diseases (Phase 4)
GATA2 Transcription Factor (Phase 2)
Genetic Diseases, Inborn (Phase 2)
Geriatrics (Phase 4)
Glioblastoma (Phase 1)
Glioma (Phase 1)
Gliosarcoma (Phase 1)
Glomerulonephritis, IGA (Phase 4)
Glomerulonephritis, Membranous (Phase 4)
Glomerulosclerosis, Focal Segmental (Phase 3)
Gout (Phase 2)
Graft Rejection (Phase 4)
Graft Survival (Phase 2)
Graft vs Host Disease (Phase 4)
Granuloma (Phase 3)
Granulomatosis with Polyangiitis (Phase 4)
Graves Disease (Phase 2/Phase 3)
Hair (Phase 2)
Healthy Volunteers (Phase 1)
Heart Diseases (Phase 4)
Heart Failure (Phase 3)
Heart Transplantation (Phase 4)
Hematologic Diseases (Phase 2)
Hematologic Neoplasms (Phase 2)
Hematopoietic Stem Cell Transplantation (Phase 4)
Hemoglobinopathies (Phase 2)
Hemoglobinuria, Paroxysmal (Phase 2)
Hepatitis (Phase 4)
Hepatitis, Alcoholic (Phase 2)
Hepatitis, Autoimmune (Phase 4)
Hepatitis C (Phase 4)
Hepatitis C, Chronic (Phase 3)
Herpesvirus 4, Human (Phase 4)
Histiocytosis, Langerhans-Cell (Phase 4)
Histiocytosis, Sinus (Phase 4)
HIV (Phase 2)
HIV Infections (Phase 4)
Hodgkin Disease (Phase 3)
Host vs Graft Reaction (Phase 3)
Hyperlipoproteinemia Type I (Phase 2/Phase 3)
Hypertension, Renal (Phase 2)
Hypertrophy, Left Ventricular (Phase 4)
Immune System Diseases (Phase 4)
Immunoglobulin Light-chain Amyloidosis (Phase 1/Phase 2)
Immunologic Deficiency Syndromes (Phase 2)
Immunosuppression Therapy (Phase 4)
Infections (Phase 2)
Inflammation (Phase 4)
Intestinal Neoplasms (Phase 4)
Intraocular Lymphoma (Phase 2)
Islets of Langerhans Transplantation (Phase 3)
Kidney Diseases (Phase 4)
Kidney Failure, Chronic (Phase 4)
Kidney Neoplasms (Phase 2)
Kidney Transplantation (Phase 4)
Kidney Tubular Necrosis, Acute (Phase 1/Phase 2)
Leukemia (Phase 3)
Leukemia, Biphenotypic, Acute (Phase 3)
Leukemia, Eosinophilic, Acute (Phase 2)
Leukemia, Hairy Cell (Phase 2)
Leukemia, Large Granular Lymphocytic (Phase 2)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 3)
Leukemia, Lymphoid (Phase 2)
Leukemia-Lymphoma, Adult T-Cell (Phase 2)
Leukemia, Mast-Cell (Phase 2)
Leukemia, Monocytic, Acute (Phase 2)
Leukemia, Myeloid (Phase 3)
Leukemia, Myeloid, Acute (Phase 3)
Leukemia, Myeloid, Chronic-Phase (Phase 3)
Leukemia, Myelomonocytic, Acute (Phase 2)
Leukemia, Myelomonocytic, Chronic (Phase 2)
Leukemia, Myelomonocytic, Juvenile (Phase 2)
Leukemia, Neutrophilic, Chronic (Phase 2)
Leukemia, Plasma Cell (Phase 2)
Leukemia, Prolymphocytic (Phase 3)
Leukemia, Prolymphocytic, B-Cell (Phase 2)
Leukemia, Prolymphocytic, T-Cell (Phase 3)
Leukodystrophy, Globoid Cell (Phase 2)
Leukodystrophy, Metachromatic (Phase 2)
Livedoid Vasculopathy (Phase 4)
Liver Cirrhosis (Phase 4)
Liver Cirrhosis, Biliary (Phase 4)
Liver Diseases (Phase 4)
Liver Transplantation (Phase 4)
Lung Diseases, Interstitial (Phase 4)
Lung Transplantation (Phase 4)
Lupus Erythematosus, Systemic (Phase 4)
Lupus Nephritis (Phase 4)
Lymphohistiocytosis, Hemophagocytic (Phase 2)
Lymphoma (Phase 3)
Lymphoma, B-Cell (Phase 2)
Lymphoma, B-Cell, Marginal Zone (Phase 2)
Lymphoma, Follicular (Phase 2)
Lymphoma, Large B-Cell, Diffuse (Phase 3)
Lymphoma, Large-Cell, Anaplastic (Phase 2)
Lymphoma, Large-Cell, Immunoblastic (Phase 3)
Lymphoma, Mantle-Cell (Phase 3)
Lymphoma, Non-Hodgkin (Phase 3)
Lymphoma, T-Cell (Phase 2)
Lymphoma, T-Cell, Peripheral (Phase 2)
Lymphomatoid Granulomatosis (Phase 2)
Lymphoproliferative Disorders (Phase 2)
Macular Degeneration (Phase 2)
Mastocytosis (Phase 2)
Medulloblastoma (Phase 1)
Melanoma (Phase 2)
Membranes (Phase 2)
Menorrhagia (Phase 3)
Metabolic Diseases (Phase 2)
Microscopic Polyangiitis (Phase 4)
Mucolipidoses (Phase 2)
Mucopolysaccharidoses (Phase 2/Phase 3)
Mucopolysaccharidosis I (Phase 2)
Mucopolysaccharidosis II (Phase 2)
Mucopolysaccharidosis III (Phase 2)
Mucopolysaccharidosis VI (Phase 2)
Mucopolysaccharidosis VII (Phase 2)
Multiple Myeloma (Phase 3)
Multiple Sclerosis (Phase 2/Phase 3)
Myasthenia Gravis (Phase 3)
Mycophenolic Acid (Phase 4)
Mycoses (Phase 2)
Myeloablative Agonists (Phase 2)
Myelodysplastic Syndromes (Phase 3)
Myeloproliferative Disorders (Phase 3)
Myocarditis (Phase 3)
Myositis (Phase 4)
Neoplasm, Residual (Phase 2)
Neoplasms (Phase 3)
Neoplasms, Germ Cell and Embryonal (Phase 1)
Neoplasms, Neuroepithelial (Early Phase 1)
Neoplasms, Plasma Cell (Phase 2)
Nephritis (Phase 2/Phase 3)
Nephrosis, Lipoid (Phase 4)
Nephrotic Syndrome (Phase 4)
Nerve Sheath Neoplasms (Phase 2)
Neural Tube Defects (Phase 2)
Neuroblastoma (Phase 2)
Neuroectodermal Tumors (Phase 1)
Neuroectodermal Tumors, Primitive (Phase 1)
Neuromyelitis Optica (Phase 4)
Neuronal Ceroid-Lipofuscinoses (Phase 2)
Neutropenia (Phase 2)
Neutrophils (Phase 2)
Organ Transplantation (Phase 4)
Pancreas Transplantation (Phase 3)
Pancreatic Neoplasms (Phase 1)
Paraproteinemias (Phase 2)
Pediatrics (Phase 1)
Pemphigoid, Benign Mucous Membrane (Phase 2/Phase 3)
Pemphigoid, Bullous (Phase 2)
Pemphigus (Phase 4)
Peripheral Blood Stem Cell Transplantation (Phase 1/Phase 2)
Peroxisomal Disorders (Phase 2)
Pharmacokinetics (Phase 1)
Plasma (Phase 3)
Plasmacytoma (Phase 2)
Plasmapheresis (Phase 4)
Polyarteritis Nodosa (Phase 4)
Polycythemia Vera (Phase 2)
Polyomavirus Infections (Phase 4)
Precancerous Conditions (Phase 2)
Primary Immunodeficiency Diseases (Phase 2)
Primary Myelofibrosis (Phase 3)
Prostatic Neoplasms (Phase 3)
Psoriasis (Phase 2)
Purpura (Phase 2)
Purpura, Thrombocytopenic, Idiopathic (Phase 3)
Radiculopathy (Phase 3)
Recurrence (Phase 3)
Renal Dialysis (Phase 4)
Renal Insufficiency (Phase 4)
Renal Insufficiency, Chronic (Phase 4)
Renal Replacement Therapy (Phase 4)
Reperfusion Injury (Phase 4)
Rhabdoid Tumor (Phase 1)
Rhabdomyosarcoma (Phase 2)
Sandhoff Disease (Phase 2)
Sarcoidosis, Pulmonary (Phase 3)
Sarcoma (Phase 1)
Sarcoma, Ewing (Phase 2)
Sarcoma, Myeloid (Phase 2)
Scleroderma, Diffuse (Phase 1)
Scleroderma, Systemic (Phase 3)
Sclerosis (Phase 2)
Severe Combined Immunodeficiency (Phase 2)
Sezary Syndrome (Phase 2)
Shwachman-Diamond Syndrome (Phase 2)
Signs and Symptoms, Digestive (Phase 4)
Sjogren's Syndrome (Phase 2)
Skin Neoplasms (Phase 4)
Small Cell Lung Carcinoma (Phase 1/Phase 2)
Sphingolipidoses (Phase 2)
Stem Cell Transplantation (Phase 2)
Stress, Psychological (Phase 1/Phase 2)
Takayasu Arteritis (Phase 3)
Tay-Sachs Disease (Phase 2)
Testicular Neoplasms (Phase 2)
Thalassemia (Phase 2)
Thrombocythemia, Essential (Phase 2)
Thrombocytopenia (Phase 2)
Tissue Donors (Phase 2)
Translocation, Genetic (Phase 2)
Transplantation (Phase 4)
Transplantation, Autologous (Phase 2)
Transplantation, Homologous (Phase 2)
Transplantation Immunology (Phase 3)
Uremia (Phase 1/Phase 2)
Urological Manifestations (Phase 1)
Uterine Cervical Neoplasms (Phase 2)
Uveitis (Phase 3)
Uveitis, Intermediate (Phase 3)
Vaccines (Phase 4)
Vaginal Neoplasms (Phase 2)
Vascular Grafting (Phase 3)
Vasculitis (Phase 4)
Waldenstrom Macroglobulinemia (Phase 3)
Wiskott-Aldrich Syndrome (Phase 2)
Wolman Disease (Phase 2)
Trial | Phase | Start Date | Organizations | Indications |
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