Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Physiological Effects of Drugs » Peripheral Nervous System Agents » Sensory System Agents » Analgesics » Analgesics, Non-Narcotic » Anti-Inflammatory Agents, Non-Steroidal
Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Therapeutic Uses » Anti-Inflammatory Agents » Anti-Inflammatory Agents, Non-Steroidal
Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Therapeutic Uses » Antirheumatic Agents » Anti-Inflammatory Agents, Non-Steroidal
Description
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. MeSH
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Phase 4 Indicated Drugs (6)
Phase 3 Indicated Drugs (1)
Other Experimental Indicated Drugs (4)
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