Trial | NCT05467384  Report issue

Official Title

Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    80
In this study, Amlodipine has been used to study its effects in newly diagnosed hypertensive patients.
The incidence of hypertension is on the rise in developing countries like Pakistan. Different medications are used to decrease blood pressure with Amlodipine as one of the first-line drugs. It was proposed that due to interaction with calcium and thus luminal cholecystokinin releasing factor; Amlodipine might increase the cholesterol level and thus cause dyslipidemia.

Objective: In this regard, this study was conducted to look into the effects of Amlodipine in newly diagnosed cases of hypertension that had received no medication previously.

Methodology: Experimental study with a healthy control group with the sample size calculated out to be 80, comprising of an equal number of enrolment into case and control groups.
Study Started
Mar 01
2016
Primary Completion
Jun 30
2017
Study Completion
Jun 30
2017
Last Update
Jul 20
2022

Drug Amlodipine

5mg/day in two divided doses

  • Other names: Norvasc

Newly Diagnosed Hypertensive patients Experimental

These are the patients that have been clearly diagnosed with diabetes for the first time.

Healthy Controls No Intervention

Healthy Control Group

Criteria 

Inclusion criteria for cases.

1) Newly diagnosed mild to moderate hypertensive. (2) Non-obese individuals. 3) Must not have received antihypertensive treatment previously. 4) Has elevated serum cholesterol levels. Exclusion criteria for cases

1) Any other major illness.

Inclusion criteria for controls

Normal lipid profile.
Normotensive (BP < 140/90mmHg). Exclusion criteria for controls

1) Any major illness.
No Results Posted