Trial | NCT03138785  Report issue

Official Title

UVX as an Adjuvant in the Treatment of Fungal Keratitis

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Unknown status

  • Study Participants

    20
In this study, investigators want to find the effect of adjuvant collagen cross-linking in the treatment of fungal keratitis
Study Started
Jan 01
2015
Primary Completion
Jun 01
2017
Anticipated
Study Completion
Jul 01
2017
Anticipated
Last Update
May 03
2017

Drug topical voriconazole / levofloxacin systemic itraconazole

starting topical voriconazole every hour tapering after 4 days , levofloxacin every 6 hours, Itraconazole 100mg /BD for 2 weeks

Radiation CXL

30 min Riboflavin prescription to the cornea followed by 30 min UV-A radiation at 3mW/cm2 associated with Riboflavin administration

  • Other names: Collagen cross-linking/ UVx

conventional treatment Experimental

In this arm, patients with documented fungal keratitis undergo conventional medical treatment.

conventional treatment +CXL Active Comparator

In this arm, patients with documented fungal keratitis undergo conventional medical treatment plus CXL, beginning on the first day

Criteria 

Inclusion Criteria:

fungal keratitis documented by culture or confocal scanning without any previous treatment

Exclusion Criteria:

Previous treatment
Thinning at presentation
Perforation
Associated with other microbial or viral keratitis
No Results Posted