Trial | NCT03049085  Report issue

Title

Effect of Preoperative Aspirin in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
Effect of Preoperative Aspirin in Patients Undergoing Off-pump Coronary Artery Bypass Grafting: A Double-blind, Placebo-controlled, Randomized Trial

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Unknown status

  • Study Participants

    300
Effect of Preoperative Aspirin in patients undergoing Off-pump Coronary Artery Bypass Grafting. A double-blind, placebo-controlled, randomized trial.
Study Started
Feb 01
2017
Primary Completion
May 31
2018
Anticipated
Study Completion
May 31
2019
Anticipated
Last Update
Feb 09
2017
Estimate

Drug Aspirin

preoperative uncoated 75 mg Aspirin is administered 2 hours prior OPCAB

  • Other names: Acetylsalicylic acid

Drug vitamin C

preoperative 75 mg Vit. C (Placebo) is administered 2 hours prior OPCAB

Aspirin group Active Comparator

a 75 mg uncoated aspirin is administered 2 hours prior to OPCAB

Placebo group Placebo Comparator

75 mg Vit. C is administered 2 hours prior OPCAB

Criteria 

Inclusion Criteria:

Eligible patients undergoing off-pump coronary artery bypass grafting (OPCAB)
Patients in whom antiplatelet therapy was stopped 5-7 days prior to OPCAB

Exclusion Criteria:

Patients undergoing on-pump coronary artery bypass grafting
Patients in whom antiplatelet therapy was not stopped 5-7 days prior to OPCAB
Intraoperative conversion to on-pump coronary artery bypass grafting
Patients with inherited blood-clotting disorders
Patients undergoing other cardiac operations
No Results Posted