Trial | NCT03004222  Report issue

Title

A Study to Determine the Effectiveness of Utilizing Intraperitoneal Bupivacaine
A Randomized Double Blinded Study to Determine the Effectiveness of Utilizing Intraperitoneal Bupivacaine: Does it Reduce Post-operative Opioid Use Following Laparoscopic Appendectomy?

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    137
The purpose of this research is to determine if spraying a local anesthetic to the cecum after a laparoscopic appendectomy decreases the amount of narcotics (pain medicine) needed after surgery and reduces the time to discharge from the hospital.
The purpose of this study is to determine the effectiveness of using intraperitoneal anesthetic during appendectomy. Subjects will be randomized to receive either 20 mL 0.5% bupivicaine or 20 mL of normal saline (placebo) instilled in the right lower quadrant at the cecum after appendix has been removed. Narcotic consumption will be tracked postoperatively. Hypothesis is that instilling local anesthetic at the cecum during a laparoscopic appendectomy will decrease the amount of narcotic a patient uses postoperatively. Secondarily, this study will attempt to determine if there is a decrease in length of stay for the subjects randomized to the anesthetic infiltration.
Study Started
Jul 31
2015
Primary Completion
Nov 30
2017
Study Completion
Nov 30
2017
Last Update
Jan 18
2018

Drug Bupivacaine

20 ml of 0.5% Bupivacaine

Drug Placebos

Local anesthetic (Bupivicaine) Experimental

The experimental arm intervention is 75 subjects will receive the study agent (20 mL of 0.5% bupivacaine) to be sprayed at the cecum after the appendix has been removed and all planned irrigation and aspiration has occurred

Placebo 20 ml Placebo Comparator

75 subjects will be treated with normal saline/placebo to be sprayed at the cecum after the appendix has been removed and all planned irrigation and aspiration has occurred

Criteria 

Inclusion Criteria:

Patients 18 years of age and older
Laparoscopic appendectomy at Metro Health Hospital

Exclusion Criteria:

Adults unable to consent Non-English speaking patients
Suspected or known malignant disease
Patients with known allergies to the local anesthetic
Utilizes opioid pain medicine for a chronic condition
Elective laparoscopic appendectomy
Known allergy or contraindication to ketorolac
No Results Posted