Trial | NCT02949583  Report issue

Title

Mouthwash of Pomegranate Against Biofilm and Gingival Inflammation in School Children
Clinical Effectiveness and Microbiological Evaluation of a Mouthwash of Pomegranate (Punica Granatum Linn.) in School Children

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    35
The mechanical control of supragingival biofilm is accepted as one of the most important measures to prevent dental caries and periodontal diseases. Nevertheless, maintaining dental surfaces biofilm-free is not an easy task. In this regard, numerous studies researches have demonstrated the effectiveness of mouthwashes containing antimicrobial active ingredients that prevent and control both supragingival biofilm and gingivitis, specially when used adjunctively to mechanical oral hygiene regimens.
In vitro and clinical researches using Punica granatum Linn shows antimicrobial and antiadherent activity against dental biofilm microorganisms. The purpose of this study was to evaluate the clinical effectiveness of a mouthwash of Punica granatum Linn. against biofilm and gingival inflammation in school children
Study Started
Mar 31
2012
Primary Completion
May 31
2012
Study Completion
May 31
2012
Last Update
Oct 31
2016
Estimate

Drug Punica granatum Linn.

Mouthwash (6,25% of Punica granatum Linn) 10mL per day during 14 days

  • Other names: Pomegranate

Drug chlorhexidine

standard anti-bacterial mouthwash Mouthwash (0,12% chlorhexidine) 10mL per day during 14 days

  • Other names: Periogard

Punica granatum Linn. Experimental

The childrens used the mouthwash contain pomegranate 6,25% twice daily for 14 days.

chlorhexidine Active Comparator

The childrens used the mouthwash contain chlorhexidine 0.12% twice daily for 14 days.

Criteria 

Inclusion Criteria:

Age group: 09-12 years old
Presence of at least 20 teeth
Simplified Oral Hygiene Index (S-OHI)≥ 1,6

Exclusion Criteria:

Use of orthodontic appliance
Recent (in the past 2 months)use of antibiotics and mouthwashes
No Results Posted