Trial | NCT02779868  Report issue

Title

Omega-3 Supplementation in Cervix Cancer Patients Undergoing Chemoradiotherapy
Effect of Omega-3 Supplementation on Body Composition, Functional Capacity, Inflammatory Profile and Quality of Life in Cervix Cancer Patients Undergoing Chemoradiotherapy

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    40
Cancer cachexia is a complex metabolic process affecting up to 80% of patients suffering from an advanced-stage cancer. Moreover, 20 to 40% of all cancer deaths are caused directly by cachexia. Recently, omega-3 fatty acids have gained interest for their beneficial effects in cancer cachexia. Moreover, nutritional supplementation enriched with omega-3 could potentially maintain body weight in cancer patients undergoing intensive treatment.

The investigators aims in this study is to evaluate the effect of omega-3 supplementation on body composition, functional capacity, inflammatory profile and quality of life in cervix cancer patients undergoing chemoradiotherapy.
Study Started
May 31
2016
Primary Completion
Jul 31
2017
Study Completion
Jul 31
2017
Last Update
Jul 25
2017

Dietary Supplement Omega-3

patients included in this group will take 2g (4 capsules) per day of eicosapentaenoic acid.

  • Other names: intervention group

Dietary Supplement Olive oil

patients included in this group will take 4 capsules per day of olive oil.

  • Other names: placebo group

Omega-3 Experimental

Group who will receive 2g eicosapentaenoic (4 capsules) acid per day during the chemoradiotherapy protocol.

Olive oil Placebo Comparator

Group who will receive olive oil per day (4 capsules) during the chemoradiotherapy protocol.

Criteria 

Inclusion Criteria:

Cervix cancer at FIGO stage II and III
Chemoradiotherapy treatment proposal (cisplatin + radiotherapy)
Nutritional diagnosis of pre-cachexia ou cachexia

Exclusion Criteria:

metastasis (FIGO stage IV)
Nutritional diagnosis of refractary cachexia
No Results Posted