Trial | NCT02394418  Report issue

Title

Effect of Sevoflurane, Propofol and Dexmedetomidine on Delirium & Neuroinflammation in Mechanically Ventilated Patients
Comparison of Sedative Effects of Sevoflurane, Propofol and Dexmedetomidine on the Clinical Course of Delirium and Neuroinflammation in Mechanically Ventilated Patients

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Withdrawn

  • Study Participants

    0
Assessment of sedative effects of sevoflurane, dexmedetomidine and propofol on the clinical course of delirium, SIRS and neuroinflammation in mechanically ventilated patients using CAM-ICU scale, GSK-3beta and protein S100b in serum.
Study Started
Sep 01
2017
Anticipated
Primary Completion
May 31
2018
Anticipated
Study Completion
Aug 31
2018
Anticipated
Last Update
Aug 15
2019

Drug Sevoflurane

Treatment of delirium by inhaled sevoflurane

  • Other names: Sevorane

Drug Propofol

Treatment of delirium by propofol i.v. infusion

  • Other names: Diprivan

Drug Dexmedetomidine

Treatment of delirium by dexmedetomidine i.v. infusion

  • Other names: Dexdor

Sevoflurane Active Comparator

Treatment of delirium by inhaled sevoflurane

Propofol Active Comparator

Treatment of delirium by propofol i.v. infusion

Dexmedetomidine Active Comparator

Treatment of delirium by dexmedetomidine i.v. infusion

Criteria 

Inclusion Criteria:

presence of delirium

Exclusion Criteria:

presence of Alzheimer's disease
any mental disorder
presence of cancer
No Results Posted