Trial | NCT02343432  Report issue

Title

Is the Efficacy of Epidural Steroid Injections Related to the Different Volume Injections?
Is the Efficacy of Epidural Steroid Injections Related to the Different Volume Injections? :A Randomised, Clinical Trial

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Indication/Condition

    Pain

  • Study Participants

    75
This study was aimed to investigate the impact of using different epidural volumes.

Patients with acute discogenic pain were included in the study.
Objectives: This study was aimed to investigate the impact of using different epidural volumes.

Methods: Seventy five patients with acute discogenic pain were included in the study.The patients were randomly assigned to three groups. All patients received a single epidural dose of triamcinolone [80 mg] and 12.5 mg bupivacaine combination. The patients in Group 1, Group 2 and Group 3 received a volume of 10 mL, 15 mL, and 20 mL by epidural injections, respectively. The efficacy of treatment was assessed with VAS (visual analog scale) [O= no pain, 10 = unbearable pain], SLET(straight leg elevation test) [0° = worst, 85° = best], and Oswestry Disability Index; ODI [0% to 20%:minimal disability , 80% to 100%:bed bound patients] before and 2 weeks after the EPSI.
Study Started
Mar 31
2008
Primary Completion
Aug 31
2008
Study Completion
Sep 30
2008
Last Update
Jan 22
2015
Estimate

Drug Triamcinolone

Triamcinolone

  • Other names: Kelanocort

Drug Epidural Volume

Epidural Volume

Drug Bupivacaine

Bupivacaine

  • Other names: Marcaine

Epidural Volume 10mL Experimental

Epidural Volume 10mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 10mL Intervention: Drug: Bupivacaine 12.5mg

Epidural Volume 15mL Experimental

Epidural Volume 15mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 15 mL Intervention: Drug: Bupivacaine 12.5mg

Epidural Volume 20mL Experimental

Epidural Volume 20mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 20 mL Intervention: Drug: Bupivacaine 12.5mg

Criteria 

Inclusion Criteria:

acute discogenic pain with less than three months duration not responding to other modalities of conservative management [NSAIDs, physiotherapy, bracing, etc.],
radiological disc bulging accompanying unilateral root impingement symptoms,
an Oswestry daily activity score more than 20 percent, and
resistance to treatment.

Exclusion Criteria:

Patients with bilateral root impingement symptoms, neurological deficits, and/or history of previous lumbar disc surgery, severe cardiac, pulmonary, gastrointestinal, renal diseases, glaucoma, urinary retention, and/or known allergy to the drugs used in the study were excluded from the study.
No Results Posted