Trial | NCT02289586  Report issue

Title

Interventional Bronchoscopy Under Noninvasive Ventilation
Interventional Bronchoscopy Under Noninvasive Ventilation for Central Airway Stenosis

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Unknown status

  • Intervention/Treatment

    propofol dezocine fentanyl midazolam remifentanil ...

  • Study Participants

    40
To evaluate the effect and safety of noninvasive ventilation assisted interventional bronchoscopy for hypoxemia patients with central airway stenosis.

With the sedation and analgesia, noninvasive ventilation assisted interventional bronchoscopy for hypoxemia patients with central airway stenosis is safe and effective, carries high satisfaction rate.
Study Started
Jul 31
2014
Primary Completion
Feb 29
2016
Anticipated
Last Update
Nov 13
2014
Estimate

Drug general anesthesia(midazolam, fentanyl，rocuronium，propofol and Remifentanil）

Procedure invasive ventilation

Procedure interventional bronchoscopy

Device noninvasive ventilation

Drug sedation(dezocine and midazolam)

hypoxemia, central airway stenosis. Active Comparator

Inclusion Criteria: (a)patients with central airway stenosis need interventional bronchoscopy (b) partial pressure of arterial oxygen (PaO2)/fraction of inspired oxygen (FiO2) ratio less than 300; Exclusion Criteria: (a) facial deformity sufficient to preclude mask fitting; (b) upper gastrointestinal bleeding; (c) upper airway obstruction; (d) acute coronary syndromes; (e) tracheostomy or endotracheal intubation(ETI) before admission; (f) need for urgent ETI due to cardiac or respiratory arrest.

hypoxemia, central airway stenosis Experimental

Inclusion Criteria: (a)patients with central airway stenosis need interventional bronchoscopy (b) partial pressure of arterial oxygen (PaO2)/fraction of inspired oxygen (FiO2) ratio less than 300; Exclusion Criteria: (a) facial deformity sufficient to preclude mask fitting; (b) upper gastrointestinal bleeding; (c) upper airway obstruction; (d) acute coronary syndromes; (e) tracheostomy or endotracheal intubation(ETI) before admission; (f) need for urgent ETI due to cardiac or respiratory arrest.

Criteria 

Inclusion Criteria:

(a)patients with central airway stenosis need interventional bronchoscopy. (b) partial pressure of arterial oxygen (PaO2)/fraction of inspired oxygen (FiO2) ratio less than 300;

Exclusion Criteria:

(a) facial deformity sufficient to preclude mask fitting; (b) upper gastrointestinal bleeding; (c) upper airway obstruction; (d) acute coronary syndromes; (e) tracheostomy or endotracheal intubation(ETI) before admission; (f) need for urgent ETI due to cardiac or respiratory arrest.
No Results Posted