Title
Anesthetic Blockades and Migraine
Effects of Anesthetic Blockades on Pain Modulation in Migraine
Phase
Phase 2Lead Sponsor
Universidad Rey Juan CarlosStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
Chronic Migraine PainIntervention/Treatment
levobupivacaine sodium chloride ...Study Participants
36Greater occipital nerve (GON) anesthetic blockades are widely used for the treatment of headaches, yet its efficacy in migraine has hardly been assessed with controlled studies. The aim of this study is to evaluate the short-term clinical efficacy of GON anaesthetic blockades in chronic migraine and to analyze their effect on pressure pain thresholds (PPTs) in different areas. We hypothesize that those patients receiving real GON anesthetic blockade will receive greater improvements in pain nociception. We will conduct a double-blind, randomized, parallel and placebo-controlled clinical trial where one group will be treated with bilateral GON blockade with bupivacaine 0,5% and the other group will be treated with placebo.
Patients will receive a bilateral greater occipital nerve blockade with bupivacaine 0,5%
Patients will receive a bilateral occipital injection with isotonic saline
Inclusion Criteria: Chronic migraine Exclusion Criteria: Other primary headaches Other secondary headaches Co-morbid medical diseases