Title
Intake of Omega 3 in Morbidly Obese Patients
The Effect of ω-3 Polyunsaturated Fatty Acids (Eicosapentaenoic Acid and Docosahexanoic Acid) on Morbidly Obese Patients
Phase
N/ALead Sponsor
Pontifical Catholic University of Rio Grande do SulStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
Morbid ObesityIntervention/Treatment
icosapent ethyl ...Study Participants
46Ingestion of capsules of omega 3 EPA and DHA, with 1.8 g of EPA and 1.2 g DHA for morbidly obese patients, will improve the inflammatory status? C-reactive protein? Weight?
Intake of EPA and DHA for the management of morbid obesity in capsules
- Reduction of inflammatory factors such as adipokines, glucose, C-reactive protein, cholesterol, weight, BMI. Will be 2 groups: cases and controls. The cases will intake of omega 3 capsules and placebo control.
Individuals of both sexes with ages between 18 and 65 years took 3g of omega 3, and 1.8g eicosapentaenoic acid (EPA) and 1.2g docosahexanoic acid (DHA) for 8 weeks.
They received gelatin (colorless) capsules. A nutritional evaluation was performed, a 24-h recordatory was applied to verify macro and micronutrients intake, biochemical evaluation before and after the intervention. Macro and micronutrients were calculated using the Avanutri 2.0 system. Clinical history was verified through a questionnaire previously filled out by a physician.
Omega 3 intake, morbid obesity
Inclusion Criteria: Men and women aged between 18-65 years, BMI > 40 kg/m2 (or > 35 kg/m2 with comorbidities), ambulatory, receiving an oral diet, with a diagnosis of metabolic syndrome, and who signed a Term of Free and Informed Consent. Exclusion Criteria: Systemic inflammatory response syndrome, coma or compromised organ, fever or infection foci, cancer with or without chemotherapy and radiotherapy, radiotherapy, inflammatory diseases of the gastrointestinal tract, transplant, trauma, surgery or hospital stay in the past 30 days use of steroids or non-steroid anti-inflammatory or immunomodulators agents or antibiotics, or those refusing to take part in the study.
