Trial | NCT01896037  Report issue

Title

Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels
Omega-3 Supplementation to Increase HDL-c Levels in Those With Tetraplegia

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    21
People with a spinal cord injury (SCI) characteristically have low levels of high-density lipoprotein-cholesterol (HDL-c; "good cholesterol") and high levels of low-density lipoprotein-cholesterol (LDL-c; "bad cholesterol"), and are at a higher risk of developing cardiovascular health problems, such as heart disease, heart attack and stroke, than the able-bodied population. A common way for able-bodied people to improve their lipid profile is through exercise; however, SCI people, especially tetraplegics, are often unable to achieve and maintain a level of exercise needed to obtain these benefits. It is therefore clinically important to find an effective, safe and inexpensive method of increasing HDL-c levels in people with chronic tetraplegia. This study will investigate the effects of omega-3 fatty acid supplementation on the lipid profile of people with tetraplegia. The investigators hypothesize that 5 months of daily consumption of high doses of omega-3 fatty acids will increase plasma levels of HDL-c in those with tetraplegia, leading to decreased risk of cardiovascular health issues.
Study Started
Jul 31
2013
Primary Completion
Jan 28
2017
Study Completion
Mar 28
2017
Last Update
May 04
2017

Dietary Supplement Omega-3 supplements

Daily omega-3 supplements of 600 mg EPA (Eicosapentaenoic acid) and 300 mg DHA (Docosahexaenoic acid) for 5 months.

Omega-3 supplements Experimental

Daily omega-3 supplements of 600 mg EPA (Eicosapentaenoic acid) and 300 mg DHA (Docosahexaenoic acid) for 5 months.

Criteria 

Inclusion Criteria:

Having chronic tetraplegia (at least on year since injury)
18 years or older
Having below normal fasting blood plasma levels of HDL-c (<1 mmol/l)

Exclusion Criteria:

Currently taking omega-3 supplements
Currently taking medications for abnormal cholesterol
Having a heart attack or stroke in the past one year
No Results Posted