Lipoproteins, HDL D008075

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Lipoproteins » Lipoproteins, HDL

Chemicals and Drugs [D] » Lipids [D10] » Lipoproteins » Lipoproteins, HDL

Description

A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.   MeSH

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