Trial | NCT01834508  Report issue

Title

3E Extension Study
A 3-year, Open-lable, Multi-center Extension Trial of Entecavir Plus Adefovir Combination Treatment for Patients Previously Treated in EXPLORE, EXCEL and EFFORT Ex Study

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Unknown status

  • Study Participants

    600
The purpose of this study is to evaluate the long-term efficacy and safety of entecavir 0.5 mg/d + adefovir 10 mg/d for treatment experienced chronic hepatitis B patients.
Study Started
Mar 31
2013
Primary Completion
Jun 30
2016
Anticipated
Study Completion
Dec 31
2016
Anticipated
Last Update
Jun 19
2014
Estimate

Drug oral entecavir 0.5mg daily and adefovir 10mg daily for 144 weeks

Treatment group Other

Criteria 

Inclusion Criteria:

Subjects who completed the EXPLORE or EXCEL studies, or subjects with hepatitis flare after treatment withdrawal in EFFORT study.
Subjects who are willing to participate the extension study.

Exclusion Criteria:

Subjects who could not compliance with the protocol judged by investigators
No Results Posted