Trial | NCT01384708  Report issue

Official Title

Evaluation of a Miniaturized Microscope Device for the Detection of Esophageal Squamous Cell Cancer

  • Phase

    Early Phase 1

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    proflavine ...

  • Study Participants

    70
The overall objective of this study is to determine whether high-resolution imaging of the esophagus during routine diagnostic upper endoscopy can assist clinicians in detecting and discriminating dysplastic (precancerous) areas. This high-resolution microendoscope (HRME) was developed by our collaborators at Rice University and provides > 1000x magnified images of the esophageal mucosa. The purpose of this study is to determine whether this device can be used to enhance the diagnostic accuracy of routine endoscopic screening for squamous cell cancer of the esophagus.
Study Started
Aug 31
2010
Primary Completion
Oct 31
2013
Study Completion
Oct 31
2013
Last Update
Jan 11
2016
Estimate

Drug proflavine

1-10 ml of proflavine (derived form dissolving 10mg proflavine hemisulfate USP in 100 ml sterile water)

  • Other names: Proflavine hemisulfate

treatment Experimental

imaging with proflavine

Criteria 

Inclusion Criteria:

known or suspected squamous cell neoplasia
18 years or older
No Results Posted