Title
Effect of Turmeric on Diabetic Nephropathy
Phase
N/ALead Sponsor
Shaheed Faghihi HospitalStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
Diabetic Nephropathy ProteinuriaIntervention/Treatment
enalapril curcuma longa losartan ...Study Participants
50The purpose of this study is to investigate whether turmeric is effective in improvement of diabetic nephropathy and in decrease in the amount of proteinuria and cytokine levels.
Diabetic nephropathy is leading cause of ESRF that many therapy recommended for it. In this study, we investigate effect of turmeric on diabetic nephropathy, thus we selected diabetic nephropathy patients and divided them into 2 groups. One group received turmeric + ACE inhibitor + Angiotensin II receptor blocker (ARB) and the second group received only ACE inhibitor + ARB.
turmeric 500 mg TID for 45 days
maximum dosage as patient tolerated for 45 days
diabetic nephropathy patient more than 300 mg/proteinuria
diabetic nephropathy more than 300 mg/day proteinuria
Inclusion Criteria: diabetic nephropathy more than 300 mg proteinuria/day age more than 18 years old Exclusion Criteria: DM type 1