Active Ingredient History

NOW
  • Now
Losartan is a selective, competitive angiotensin II receptor type 1 (AT1) antagonist. Losartant is recommended as one of several preferred agents for the initial management of hypertension. Administration of losartan reduces the risk of stroke in patients with hypertension and left ventricular hypertrophy. Losartan is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension.   NCATS

  • SMILES: CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)c3ccccc3c4nnn[nH]4
  • InChIKey: PSIFNNKUMBGKDQ-UHFFFAOYSA-N
  • Mol. Mass: 422.92
  • ALogP: 4.27
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.0673 - $4.9747

Australia

$0.1421 - $0.2021
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

(2-butyl-4-chloro-1-{[2'-(1h-tetrazol-5-yl)biphenyl-4-yl]methyl}-1h-imidazol-5-yl)methanol | 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole | allisartan | cozaar | dup-753 | dup 89 | hgp0608 | hydrochlorothiazide - losartan | hydrochlorothiazide, losartan drug combination | hydrochlorothiazide - losartan potassium | hydrochlorothiazide, losartan potassium drug combination | hyzaar | lorsartan | lortaan | lorzaar | losaprex | losartan | losartan monopotassium | losartan monopotassium salt | losartan potassium | mk-0954 | mk0954a | mk-954h | preminent

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